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Mary L Schneider |
Our research program focuses on behavioral and neurobiological effects from fetal alcohol exposure alone or in combination with prenatal stress. We study rhesus monkeys, examining growth and development, learning and memory, and stress reactivity across the life span. We also use state-of-the-art neuroimaging techniques to elucidate possible abnormalities in neural processing. We assess dopamine system function, using positron emission tomography, to determine whether altered DA function might underlie some of the motor, learning, and neuroendocrine outcomes associated with these prenatal treatments. We have recently expanded our nonhuman primate model to examine the neurochemical and developmental basis for sensory regulation disorders. Our fetal alcohol work is funded by the National Institute on Alcohol Abuse and Alcoholism and our sensory regulation work is funded by the Wallace Foundation.
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Schneider ML, Moore CF, Barnhart TE, Larson JA, DeJesus OT, Mukherjee J, Nickles JR, Converse AK, Roberts AD, Kraemer GW (2005) Moderate level prenatal alcohol exposure alters striatal dopamine system function in rhesus monkeys. Alcoholism: Clinical and Experimental Research, 29 (9), 1685-1697. Schneider, M. L., Champoux, M., & Moore, C. F. (in press). Neurobehavioral assessment of non-human primate neonates. To be published in G. P. Sackett (Ed.), Developments in Primatology: Progress and prospects: Kluwer Academic/Plenum Publishers Converse, A. K., Barnhart, T., Dabbs, K. A., DeJesus, O. T., Larson, J. A., Nickles, R. J., Schneider, M.L., Roberts, A.D. (2004). PET Measurement of rCBF in the presence of a neurochemical tracer. Journal of Neuroscience Methods, 132, 199-208. Roberts, A. D., Moore, C. F., DeJesus, O. T., Barnhart, T. E., Larson, J. A., Mukherjee, J., Schneider, M.L. (2004). Prenatal stress, moderate fetal alcohol, and dopamine system function in rhesus monkeys. Neurotoxicology and Teratology, 26, 169-178. Schneider, M. L., Moore, C. F., & Kraemer, G. W. (2003). On the relevance of prenatal stress to developmental psychopathology. In D. Cicchetti & E. F. Walker (Eds.), Neurodevelopmental Mechanisms in Psychopathology (pp. 155-186). Cambridge, UK: Cambridge University Press. Schneider, M.L., Moore, C.F., Kraemer, G.W., Roberts, A.D., & DeJesus, O.T. (2002). The impact of prenatal stress, fetal alcohol exposure, or both on development: Perspectives from a primate model. Psychoneuroendocrinology, 27, 285 298. Schneider, ML, Moore, C, Kraemer, GW (2001). Moderate alcohol during pregnancy: Learning and behavior in adolescent monkeys. Alcoholism: Clinical and Experimental Research. 25 (9).
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