Date:
March 16, 2007
Time: Noon to 1:00
Title: "Anxiety, Social Interactions, and the Role of Genetic
Background in a Mouse Model of Fragile X Syndrome"
Speaker: Richard Paylor, PhD
Baylor College of Medicine
Where: Waisman
Conference Center
Room T216, Second Floor, North Tower
About the Talk:
The loss of FMR1 gene function causes Fragile X syndrome (FXS), a common mental retardation syndrome. Anxiety and abnormal social behaviors are prominent features of FXS in humans. To better understand the role of FMR1 in these behaviors, we analyzed anxiety-related and social behaviors in Fmr1 knockout (KO) mice. Over the past several years we have demonstrated that Fmr1 KO mice display a complex set of abnormal social interactions that are influenced by experience, and genetic background. Taken together we believe that these findings suggest that Fmr1 KO mouse is a relevant animal model for both non-autistic-like, and autistic-like traits seen in FXS.
For Further Information: Contact Teresa Palumbo at 263-5837 or
palumbo@waisman.wisc.edu
The Waisman Center Seminar
Series is partially funded by the
Friends of the Waisman Center and NIH grant
P30 HD003352.
