/ Faculty / Waisman Center

Andrew Alexander

Andrew L. Alexander
Ph.D., University of Arizona, Tucson
Faculty Co-Director, Brain Imaging Core
Associate Professor of Medical Physics & Psychiatry
Director of MR Physics Research, Waisman Laboratory for Brain Imaging and Behavior

Contact Information
Waisman Center
1500 Highland Avenue, Room T135
Madison, WI 53705
(608) 265-8233
Fax: 608-262-9440
E-Mail: aalexander@waisman.wisc.edu http://brainimaging.waisman.wisc.edu/

My research is focused on the use of Magnetic Resonance Imaging (MRI) for mapping and measuring the functional and structural organization of the human brain. These techniques are being used to investigate the brain in both typically developing individuals and subjects with developmental disorders including autism. Functional MRI (fMRI) is used to assess brain regions associated with cognition and affect and their dysfunctions in these populations. Diffusion tensor MRI (DT-MRI) is being used to study the patterns of structural connectivity between brain activity regions. Anatomic imaging methods are used to assess longitudinal structural changes in brain regions. These measurements are ultimately compared with measures of affect, behavior and cognition in specific population groups.

Thottakara P, Lazar M, Johnson SC, Alexander AL. Probabilistic connectivity and segmentation of white matter using tractography and cortical templates. Neuroimage 29(3):868-878(2006).

The Brain During Life in Autism: Advances in Neuroimaging Research. Book Chapter. Lainhart JE, Lazar M, Bigler ED, Alexander AL. In Recent Developments in Autism Research. Casanova MF, editor. Nova Science Publishers (2005).

Lazar M, Lee JH, Alexander AL. Consistent cylindrical asymmetries in the diffusion tensor of the human brain. Magn Reson Med 54(4): 860-7 (2005).

Lazar M, Alexander AL. Bootstrap white matter tractography (BOOT-TRAC). Neuroimage 24:524-32 (2005).

Wu YC, Field AF, Badie B, Alexander AL. Qualitative analysis of diffusion tensor orientation: theoretical framework. Magn. Reson. Med. 52(5):1146-55 (2004).

Lazar M, Alexander AL. An error analysis of white matter tractography methods: Synthetic diffusion tensor field simulations. Neuroimage 20(2): 1140-53 (2003).

Lazar M, Weinstein DM, Tsuruda JS, Hasan KM, Arfanakis K, Meyerand ME, Badie B, Rowley H, Haughton V, Field A, Witwer B, Alexander AL. White matter tractography using tensor deflection. Human Brain Mapping 18:306-21 (2003).

Witwer BP, Moftakhar R, Hasan KM, Deshmukh P, Arfanakis K, Haughton V, Rowley H, Field A, Noyes J, Meyerand ME, Alexander AL, Badie B. Diffusion tensor imaging of white matter tracts in patients with cerebral neoplasms. J. Neursurgery 97:568-75 (2002).

Alexander AL, Hasan K, Lazar M, Tsuruda JS, Parker DL. Analysis of partial volume effects in diffusion-tensor MRI. Magn. Reson. Med. 45:770-80 (2001).

Alexander AL, , Hasan K, Kindlmann G, Parker DL, Tsuruda JS. A geometric comparison of diffusion anisotropy measures. Magn. Reson. Med. 44:283-91 (2000).

Click to search National Library of Medicine and PubMed for other publications by Dr. Alexander

July 1, 2008