NIH or NSF Funded Research Projects

IDDRC Groups
MGS: Molecular and Genetic Sciences Group
CCS: Communication and Cognitive Sciences Group
SAS: Social and Affective Sciences Group

Marsha Mailick Seltzer, PhD (SAS)

1. Impacts of Parenting Adolescents and Adults with Autism
2. Family Adaptation to Fragile X Syndrome: Adolescents and Adults
3. The Effect of Nonnormative Parenting on the Normative Transitions of Aging
4. Aging in Adults with Down Syndrome
5. Prevalence of the Fragile X Premutation

Leonard Abbeduto, PhD (CCS)

6. Language Development in Fragile X Syndrome
7. Social-Affective Bases of Word Learning in Fragile X Syndrome and Autism
8. Cognitive Precursors of Language Impairment in Down Syndrome

Andrew Alexander, PhD (SAS)
9. Diffusion MRI of the Human Brain
10. Atypical Late Neurodevelopment in Autism: A Longitudinal MRI and DTI Study
11. Diffusion Tensor Imaging of Amygdalo-Frontal Pathways

Ruth Benedict, PhD (CCS)
12. Outcomes of Interventions for Spasticity Management among Children and Young Adults with Cerebral Palsy and their Caregivers

Lawrence Berger, PhD (SAS)
13. Maternal Re-Partnering, Parenting Behaviors, and Child Development

Craig Berridge, PhD (MGS)
14. Low-Dose Methylphenidate and the Prefrontal Cortex

Anita Bhattacharyya, PhD (MGS)
15. Generation of Trisomy 21 Induced Pluripotent Stem Cells
16. Generation of Human Trisomy 21 Pluripotent Cells

Erik Carter, PhD (SAS)
17. Secondary and Postsecondary Outcomes

Qiang Chang, PhD (MGS)

18. In Vivo Function of Neuronal Activity-induced MeCP2 Phosphorylation
19. Studying the Molecular Mechanism of Rett Syndrome
20. Therapeutic Potential of TrkB Activation in RTT

Bradley Christian, PhD (SAS)
21. A Novel PET Radiotracer to Study 5HT-1A Receptors in Fetal Alcohol Exposure
22. [F-18]Mefway PET to Measure 5-HT1A Receptors in Gene x Environment Interactions
23. Natural History of Amyloid in Adults with Down Syndrome

Christopher Coe, PhD  (MGS)

24. Maternal Flu Infection and Brain Development in Primate
25. Brain & Behavior in Monkeys Born to Young Mothers

Kim Dalton, PhD (SAS)
26. Face Processing and Brain Function Associated with Autistic Symptoms in Fragile X

Richard J. Davidson, PhD  (SAS)
27. Neural Substrates of Affective Style and Emotion Regulation
28. Neural Bases of Emotion Regulation and Dysregulation in Adolescence

John Denu, PhD (MGS)
29. Reversible Protein Acetylation and Chromatin Function

Maureen Durkin, PhD (SAS)
30. Epidemiology of SBCAD Deficiency in Hmong-Americans

Jan Edwards, PhD (CCS)
31., 32. Cross Language Investigation of Phonological Development ARRA Summer Supplement - Cross Language Investigation of Phonological Development
33. Using Machine Learning to Model the Interplay of Production Dynamics and Perception Dynamics in Phonological Acquisition

Susan Ellis Weismer, PhD (CCS)
34. Early Language Development within the Autism Spectrum

Peter Ferrazzano, MD (MGS)
35. MRI Biomarkers of Pediatric Brain Injury and Neuroprotection

Michael Fleming, MD, MPH (SAS)
36. Alcohol Biomarkers in General Clinical Settings

David Gamm, MD, PhD (MGS)
37. Human Stem Cell-based Therapies for Age-related Macular Degeneration
38. Customized iPS Cell Therapy for Recessive Monogenetic RDD

H. Hill Goldsmith, PhD (SAS)
39. Longitudinal Twin Studies of Early Emotional Development
40. A Twin Study of Autism Spectrum Disorder
41. Risk for Child Psychopathology: A Twin Study Perspective
42. Adolescent Anxiety: A Longitudinal Twin Study Perspective

Matthew Goupell, PhD (CCS)
43. Speech Understanding and Signal Detection in Noise in Bilateral Cochlear Implants

Sam Gubbels, MD (MGS)
44., 45. Stem Cell-Based Therapies for Hearing Loss: Directed Differentiation and In Utero Transplantation of Pluripotent Stem Cells for Auditory Hair Cell Regeneration  – CTSA KL2
Inner Ear Hair Cell Generation Using Directed Differentiation – CTSA Pilot

Derek Hei, PhD (MGS)
46. Methods of Large Scale Production of HES Cells

Katherine Hustad, PhD  (CCS)
47. Speech Development in Children with Cerebral Palsy
48. Communication Development in Children with Cerebral Palsy

Jeffrey Johnson, PhD (MGS)
49. The Nrf2-ARE Pathway in Modulating Parkinson’s Disease
50. Transthyretin's Regulatory Role in Beta-Amyloid Aggregation and Toxicity
51. The Nrf2-ARE Pathway in Amyotrophic Lateral Sclerosis

Sterling Johnson, PhD (CCS)
52. fMRI of Vulnerable Brain Areas in People at Risk for AD

Ned Kalin, MD (SAS)
53. Development and Regulation of Emotion in Primates
54. Developmental Mechanisms Underlying the Risk to Develop Anxiety and Depression
55. Brain Mechanisms Mediating Genetic Risk Factors for Anxiety and Depression

Margarita Kaushanskaya, PhD (CCS)
56. Word Learning and Word Knowledge in Monolingual and Sequential Bilingual Children

Sunduz Keles, PhD
57. Statistical Methods for the Analysis of ChIP-chip Data

Lingjun Li, PhD (MGS)
58. Mass Spectrometric Studies of Neuropeptides in Feeding

Ruth Litovsky, PhD (CCS)
59. Spatial Hearing in Children with Normal Hearing and Bilateral Cochlear Implants
60. Binaural Sensitivity and Spatial Hearing in Bilateral Cochlear Implant Users

James Malter, MD (MGS)
61. Pin1 in Synaptic Plasticity and Translation

Albee Messing, VMD, PhD (MGS)
62. Analyses and Applications of GFAP Transcription
63. Mouse Models of Alexander Disease
64. Mouse Models of Alexander Disease (Project 2 of Alexander Disease: Cellular and Molecular Mechanisms)

Julie Poehlmann, PhD (SAS)
65. The Development of Self-Regulation in High Risk Infants

Seth Pollak, PhD (SAS)
66. Neurobehavioral Correlates of Early Deprivation
67., 68. Emotion Processing: Risk for Psychopathology in Children Emotion Processing: Risk for Psychopathology- Diversity Supplement

Jenny Saffran, PhD (CCS)
69., 70. Statistical Learning in Language Acquisition Statistical Learning in Language Acquisition - ARRA Supplement
71. Prediction as a Mechanism of Infant Language Acquisition

Mary Schneider, PhD (SAS)
72. Fetal Alcohol Effects in Monkeys: Dopamine and Behavior
73. Moderate Level Prenatal Alcohol Exposure in Primates

Lawrence Shriberg, PhD (CCS)  (SAS)
74. Developmental Phonological Disorders
75. Developmental Phonological Disorders - ARRA Supplement

Susan Smith, PhD (MGS)
76. Craniofacial Morphogenesis in Prenatal Alcohol Exposure
77. Is Maternal Iron Status a Risk Factor in Fetal Alcohol Syndrome?

Dandan Sun, MD, PhD (MGS)
78., 79. Na+-K+-CI- Cotransporter in Cerebral Ischemia ARRA Supplement - Na+-K+-CI- Cotransporter in Cerebral Ischemia
80. The Role of Na+/H+ Exchanger in Cerebral Ischemia

John Svaren, PhD (MGS)
81., 82. Genetic Control of Myelination by EGR2 and NAB Proteins ARRA Summer Supplement - Genetic Control of Myelination by EGR2 and NAB Proteins
83. Mapping Functional Elements

Houri K. Vorperian, PhD (CCS)
84. MRI & CT Studies of the Developing Vocal Tract

Cara Westmark, PhD (MGS)
85. Utilization of Fenobam to Reduce APP and Ab in Fragile X Mice

Whitney Witt, PhD (SAS)
86. Interactions Between Childhood Illness and the Family

Jerry Yin, PhD (MGS)
87. Sleep and Memory Formation in Drosophila

Su-Chun Zhang, MD, PhD (MGS)
88. Replacement of Motor Neurons and Astrocytes in ALS Using Human Embryonic Stem Cells (Project 3 of Stem Cell and Growth Factor Therapy for ALS)
89. Common Human Stem Cell Lines for Inducible Gene Expression and Knockdown
90. Neural Specification of Human Embryonic Stem Cells
91. Disease Pluripotent Stem (iPS) Cells
92. Modeling Human Motor Neuron Degeneration Using Stem Cells