Spina bifida is the most complex birth defect compatible with life. It can affect every major body system. Some children with spina bifida will experience several of these associated diagnoses and secondary conditions; other may exhibit just a few. The degree of impact each diagnosis has will vary from child to child and can change as the child grows. Below is a list of the most common associated diagnosis. This is followed by a list of the major body systems and the potential impact spina bifida myelomengocele may have on these systems.