Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Arezoo Movaghar earned her master’s degree in computer science and artificial intelligence. She built models based on the plentiful data found in medical records. So, when she came to UW–Madison as a PhD student and joined a research group, it surprised Movaghar to find out just how much data researchers in other fields collect.
By Adityarup “Rup” Chakravorty New insights into the molecular machinations behind fragile X syndrome, the most common inherited intellectual disability, may help researchers develop potential therapies. Fragile X is a genetic condition that affects one in 4,000 males and one in 6,000 females. It’s linked to variations in the gene that makes a protein called …
This study compared gesture use in young children with DS and TD as well as how mothers respond to child gestures based on child age and diagnosis.
Click. Click. Click. What’s that sound? It’s Waisman Center investigator Sriram Boothalingam exploring ways to develop more comprehensive and reliable hearing tests. To test for several types of hearing loss, audiologists use a small earphone to introduce sounds – like clicks – into the ear. Then they monitor for sounds, called otoacoustic emissions, that the …
How does social information affect the perception of taste early in life? Does mere knowledge of other people’s food preferences impact children’s own experience when eating? In Experiment 1, 5- and 6- year- old children consumed more of a food described as popular with other children than a food that was described as unpopular with other children, even though the two foods were identical.
Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most speech and language impairments remain unexplained at the molecular level.
A new study of children with cerebral palsy could help ease the speech and language challenges many of these children face as they get older.
We present and characterize a robust method for rapid, scarless introduction or correction of disease-associated variants in hPSCs using CRISPR/Cas9. Utilizing non-integrated plasmid vectors that express a puromycin N-acetyl-transferase (PAC) gene, whose expression and translation is linked to that of Cas9, we transiently select for cells based on their early levels of Cas9 protein.
