Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Alexander disease (AxD) is a devastating leukodystrophy caused by gain-of-function mutations in GFAP, and the only available treatments are supportive. Recent advances in antisense oligonucleotide (ASO) therapy have demonstrated that transcript targeting can be a successful strategy for human neurodegenerative diseases amenable to this approach.
Title: Association between FMR1 CGG Repeat Number Polymorphism and Phenotypic Variation in the General Population Legend: Associations between CGG repeat lengths and phenotypes. (A) Linear association with IQ. (B) Linear association with college graduate (males only). (C) Curvilinear association with age at menopause (females only). (D) Curvilinear association with the number of biological children (females only). (E) …
Lauren Bishop, PhD, an assistant professor in the School of Social Work and a Waisman Center investigator, was recently honored with the 2022 Deborah K. Padgett Early Career Achievement Award from the Society for Social Work and Research.
Si bien el entrenamiento de balance puede no parecer divertido para la mayoría de los adolescentes, los videojuegos generalmente sí lo son.
Title: A Gene‐Environment Interaction Study of Polygenic Scores and Maltreatment on Childhood ADHD Legend: The interaction between a categorized ADHD polygenic score (PGS) and maltreatment factor score was insignificant, although the main effects of both were statistically significant (not shown). Not shown: The categorized ADHD PGS was derived based on an empirically tested cut-point that …
While balance training may not necessarily sound fun to most adolescents, video games typically do. And for adolescents with autism spectrum disorder, video games that improve their balance by teaching them yoga and tai chi poses also improves their posture, reduces the severity of their autism symptoms and influences the structure of their brains.
English Por Emily Leclerc, Escritora Científica, Waisman Center Tiaunta Martin es una orgullosa madre de tres hijos. Son de ojos brillantes, enérgicos y, por lo general, un torbellino de caos. Su hijo del medio, Benjamin, apodado Benji, es un niño inquieto de seis años que mantiene a Tiaunta en alerta constante. “Es el niño más …
Our knowledge to date about structural brain development across the lifespan in ASD comes mainly from cross-sectional studies, thereby limiting our understanding of true age effects within individuals with the disorder that can only be gained through longitudinal research.
