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Waisman Lecture – Mustafa Sahin, MD, PhD – “Mechanism-Based Biomarker and Treatment Trials in Tuberous Sclerosis”
April 26 @ 12:00 pm - 1:00 pm
Mustafa Sahin, MD, PhD
Boston Children’s Hospital
About the Speaker: Mustafa Sahin is a developmental neurobiologist and a pediatric neurologist at Boston Children’s Hospital and Harvard Medical School. He received his Sc.B. degree from Brown University, his M.D. and Ph.D. from Yale School of Medicine. He completed a pediatrics residency at Children’s Hospital of Philadelphia and a child neurology residency at Boston Children’s Hospital. Sahin is a Professor at Harvard Medical school and the Rosamund Stone Zander Chair at Boston Children’s Hospital. At Boston Children’s, Sahin is the Director of the Translational Research Program and the Translational Neuroscience Center. Sahin has established and directs the Multidisciplinary Tuberous Sclerosis Program at Boston Children’s Hospital. Work in his lab has identified the mechanisms by which tuberous sclerosis leads to miswiring of neurons in the brain and potential therapies for this disorder. The lab uses a combination of human neurons in culture, animal models and clinical studies and has generated several lines of evidence showing that TSC/mTOR pathway plays crucial roles in axon specification, guidance, myelination and regeneration. Current research focuses on translating these preclinical findings into the clinic and developing treatments for epilepsy and autism associated with activation of the mTOR pathway. He directs two national consortia to study biomarkers and comparative pathobiology of TSC and related neurodevelopmental disorders.
For Further Information: Contact Teresa Palumbo at 608.263.5837 or firstname.lastname@example.org
The seminar series is funded by the John D. Wiley Conference Center Fund, the Friends of the Waisman Center and NIH grant U54 HD090256.