We are dedicated to the use of neuroscience methods to better understand psychiatric disorders. Research methods include psychophysiology, functional MRI, PET/MR, eye-tracking, and behavioral approaches. Our strategy is to first validate methods in non-clinical contexts, then to apply paradigms in psychiatric conditions, and finally to test our measures as potential mechanistic endpoints in clinical trials.
I am physician scientist active both in basic research and clinical practice. My research interests are to 1) uncover the genetic and epigenetic bases of neurodevelopmental disorders or rare diseases with neurodevelopmental defects; 2) model genetic diseases using human patients derived cellular models and genetic mutant mice; 3) understand the circuit and molecular mechanisms underlying autism spectrum disorder; 4) develop novel molecular and epigenetic targeted therapies for genetic and epigenetic diseases.