Richard J Davidson
Faculty Core Director, Brain Imaging Core
William James & Vilas Professor of Psychology & Psychiatry
1500 Highland Avenue
Madison, WI 53705
Laboratory for Affective Neuroscience
Waisman Laboratory for Brain Imaging and Behavior
Center for Investigating Healthy Minds
Research in my laboratory is focused on cortical and subcortical substrates of emotion and affective disorders, including depression and anxiety. We study normal adults and young children, and those with, or at risk for, affective and anxiety disorders. We use quantitative electrophysiology, positron emission tomography and functional magnetic resonance imaging to make inferences about patterns of regional brain function. A major focus of our current work is on interactions between prefrontal cortex and the amygdala in the regulation of emotion in both normal subjects and patients with affective and anxiety disorders.
Shackman AJ, Fox AS, Oler JA, Shelton SE, Davidson RJ, Kalin NH. (2013) Neural mechanisms underlying heterogeneity in the presentation of anxious temperament. Proceedings of the National Academy of Sciences U S A. Proc Natl Acad Sci U S A. 2013 Apr 9;110(15):6145-50.
Rosenkranz MA, Davidson RJ, Maccoon DG, Sheridan JF, Kalin NH, Lutz A. (2013) A comparison of mindfulness-based stress reduction and an active control in modulation of neurogenic inflammation. Brain, Behavior, and Immunity. 27(1):174-84.
Heller AS, Johnstone T, Light SN, Peterson MJ, Kolden GG, Kalin NH, Davidson RJ. (2013) Relationships between changes in sustained fronto-striatal connectivity and positive affect in major depression resulting from antidepressant treatment. American Journal of Psychiatry. Am J Psychiatry. 2013 Feb 1;170(2):197-206.
Burghy CA, Stodola DE, Ruttle PL, Molloy EK, Armstrong JM, Oler JA, Fox ME, Hayes AS, Kalin NH, Essex MJ, Davidson RJ, Birn RM. (2012) Developmental pathways to amygdala-prefrontal function and internalizing symptoms in adolescence. Nature Neuroscience. 15(12):1736-41.
Levinson DB, Smallwood J, Davidson RJ. (2012) Social influences on neuroplasticity: Stress and interventions to promote well-being. Psychological Science. Mar 14.
Lapate RC, Lee H, Salomons TV, van Reekum CM, Greischar LL, Davidson RJ. (2012) Amygdalar function reflects common individual differences in emotion and pain regulation success. Journal of Cognitive Neuroscience. Jan;24(1):148-58.
Abercrombie HC, Jahn AL, Davidson RJ, Kern S, Kirschbaum C, Halverson J. (2011) Cortisol's effects on hippocampal activation in depressed patients are related to alterations in memory formation. Journal of Psychiatric Research. Jan;45(1):15-23.
Shackman AJ, Maxwell JS, McMenamin BW, Greischar LL, Davidson RJ. (2011) Stress potentiates early and attenuates late stages of visual processing. Journal of Neuroscience. Jan 19;31(3):1156-61.
Oler JA, Fox AS, Shelton SE, Rogers J, Dyer TD, Davidson RJ, Shelledy W, Oakes TR, Blangero J, Kalin NH. (2010) Amygdalar and hippocampal substrates of anxious temperament differ in their heritability. Nature. Aug 12;466(7308):864-8.
Vandehey NT, Moirano JM, Converse AK, Holden JE, Mukherjee J, Murali D, Nickles RJ, Davidson RJ, Schneider ML, Christian BT. (2010) High-affinity dopamine D-2/D-3 PET radioligands F-18-fallypride and C-11-FLB457: A comparison of kinetics in extrastriatal regions using a multiple-injection protocol. Journal of Cerebral Blood Flow & Metabolism. 30(5):994-1007.
Fox AS, Shelton SE, Oakes TR, Converse AK, Davidson RJ and Kalin NH. (2010) Orbitofrontal Cortex Lesions Alter Anxiety-Related Activity in the Primate Bed Nucleus of Stria Terminalis. Journal of Neuroscience. 30:7023-7027.
Vandehey NT, Garell PC, Hampel JA, Murali D, Smith EM, Davidson R, Converse AK, Nickles RJ and Christian BT. (2009) PET measurement of changes in D2/D3 dopamine receptor binding in a nonhuman primate during chronic deep brain stimulation of the bed nucleus of the stria terminalis. Journal of Neuroscience Methods. 176:129- 135.
Christian BT, Vandehey NT, Fox AS, Murali D, Oakes TR, Converse AK, Nickles RJ, Shelton SE, Davidson RJ and Kalin NH. (2009) The distribution of D2/D3 receptor binding in the adolescent rhesus monkey using small animal PET imaging. Neuroimage. 44:1334-1344.