Akihiro Ikeda

Akihiro Ikeda, DVM, PhD

DVM, University of Tokyo, Japan
PhD, University of Tokyo, Japan
Associate Professor, Genetics

Contact Information:

Laboratory of Genetics
425-G Henry Mall
Room 5322
Madison, WI 53706
McPherson Eye Research Institute
UW Laboratory of Genetics

Research Statement

Akihiro Ikeda has over 20 years of experience in molecular biology and mouse genetics, and has run NIH-funded research projects for the past 5 years. The broad object of Ikeda's research is to understand the molecular mechanisms causing human diseases associated with synaptic functional and structural defects and neurodegeneration. Ikeda studies mouse models of such diseases using a combination of molecular and genetic approaches, one major approach being identification of genetic modifiers.

Representative Publications

Maddox DM, Ikeda S, Ikeda A, Zhang W, Krebs MP, Nishina PM, Naggert JK. (2012) An Allele of Microtubule-Associated Protein 1A (Mtap1a) Reduces Photoreceptor Degeneration in Tulp1 and Tub Mutant Mice. Investigative Ophthalmology & Visual Science. Mar 26;53(3):1663-9.

Kawakami-Schulz SV, Verdoni AM, Sattler SG, Ikeda A, Ikeda S. (2012) Differences in corneal phenotypes between destrin mutants are due to allelic difference and modified by genetic background. Molecular Vision. 18:606-16.

Griep AE, John MC, Ikeda S, Ikeda A. (2011) Gene targeting in the mouse. Methods in Molecular Biology. 770:293-312.

Verdoni AM, Schuster KJ, Cole BS, Ikeda A, Kao WW, Ikeda S. (2010) A pathogenic relationship between a regulator of the actin cytoskeleton and serum response factor. Genetics. Sep;186(1):147-57.

Johnson BA, Cole BS, Geisert EE, Ikeda S, Ikeda A. (2010) Tyrosinase is the modifier of retinoschisis in mice. Genetics. Dec;186(4):1337-44.