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Waisman Center
Waisman Center
Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
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  2. Alzheimer's Disease

Alzheimer's Disease

Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome

PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer’s Disease

Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer’s Disease

Moderate Physical Activity is Associated with Cerebral Glucose Metabolism in Adults at Risk for Alzheimer’s Disease.

Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome

Heightened extended amygdala metabolism following threat characterizes the early phenotypic risk to develop anxiety-related psychopathology

BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer’s Prevention

Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease

Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation

Improved proteostasis in the secretory pathway rescues Alzheimer’s disease in the mouse

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