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Waisman Center
Waisman Center
Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
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  2. Rett Syndrome

Rett Syndrome

Regulation of neural differentiation, synaptic scaling and animal behavior by MeCP2 phosphorylation

Loss of MeCP2 in immature neurons leads to impaired network integration.

Mechanism and consequence of abnormal calcium homeostasis in Rett syndrome astrocytes

CREB Signaling Is Involved in Rett Syndrome Pathogenesis.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome.

Misregulation of Alternative Splicing in a Mouse Model of Rett Syndrome

Inhibition of miR-15a Promotes BDNF Expression and Rescues Dendritic Maturation Deficits in MeCP2-Deficient Neurons

Reduced cortical activity due to a shift in the balance between excitation and inhibition in a mouse model of Rett syndrome

Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2

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