AAV2.7m8 transduction of stage 2 human retinal organoids induces highly variable responses in innate and inflammatory gene expression and cytokine secretion
Metabolic stress and early cell death in photoreceptor precursor cells following retinal transplantation
Evaluation of subretinally delivered Cas9 ribonucleoproteins in murine and porcine animal models highlights key considerations for therapeutic translation of genetic medicines
Robust generation of photoreceptor-dominant retinal organoids from porcine induced pluripotent stem cells
Heterogeneity in the progression of retinal pathologies in mice harboring patient mimicking Impg2 mutations
Micromolded honeycomb scaffold design to support the generation of a bilayered RPE and photoreceptor cell construct
Re-formation of synaptic connectivity in dissociated human stem cell-derived retinal organoid cultures
Human retinal organoids harboring IMPG2 mutations exhibit a photoreceptor outer segment phenotype that models advanced retinitis pigmentosa