DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome

Bhattacharyya, PhD, A. DSCAM/PAK1 Pathway Suppression Reverses Neurogenesis Deficits in IPSC-Derived Cerebral Organoids from Patients With Down Syndrome.
Tang, X. Y., Xu, L., Wang, J., Hong, Y., Wang, Y., Zhu, Q., Wang, D., Zhang, X. Y., Liu, C. Y., Fang, K. H., Han, X., Wang, S., Wang, X., Xu, M., Bhattacharyya, A., Guo, X., Lin, M., & Liu, Y. (2021). DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome. The Journal of clinical investigation, 131(12), e135763. https://doi.org/10.1172/JCI135763