Waisman Center
Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.

Hypothalamic mTORC2 is essential for metabolic health and longevity

Puglielli, MD, PhD, L. Hypothalamic MTORC2 Is Essential for Metabolic Health and Longevity.

Chellappa K, Brinkman JA, Mukherjee S, Morrison M, Alotaibi MI, Carbajal KA, Alhadeff AL, Perron IJ, Yao R, Purdy CS, DeFelice DM, Wakai MH, Tomasiewicz J, Lin A, Meyer E, Peng Y, Arriola Apelo SI, Puglielli L, Betley JN, Paschos GK, Baur JA, Lamming DW. (2019). Hypothalamic mTORC2 is essential for metabolic health and longevity.  Aging Cell, 18(5):e13014. doi: 10.1111/acel.13014.