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Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phenotypes

Hagemann, PhD, T. L., and A. Messing, VMD, PhD. Pexidartinib Treatment in Alexander Disease Model Mice Reduces Macrophage Numbers and Increases Glial Fibrillary Acidic Protein Levels, Yet Has Minimal Impact on Other Disease Phenotypes.
Boyd, M. M., Litscher, S. J., Seitz, L. L., Messing, A., Hagemann, T. L., & Collier, L. S. (2021). Pexidartinib treatment in Alexander disease model mice reduces macrophage numbers and increases glial fibrillary acidic protein levels, yet has minimal impact on other disease phenotypes. Journal of neuroinflammation, 18(1), 67. https://doi.org/10.1186/s12974-021-02118-x