Additional Resources
- Guide for the Care and Use of Laboratory Animals – NIH (pdf)
- UW Research Animal Resources Center
- AVMA Guidelines on Euthanasia
- International Knockout Mouse Consortium (IKMC)
- Michael Festing’s web site on experimental design
- Power analysis for calculating number of animals needed for experiment
Purpose: For justification of the species and number of animals proposed, the Guide states that in the preparation of the protocol by the researcher and its review by the IACUC, whenever possible, the number of animals and experimental group sizes should be statistically justified [p, 25, 4th in a list of 15 items], and that while the responsibility for scientific merit review normally lies…www.rarc.wisc.edu
