Waisman Lecture – Paul Hagerman, MD, PhD – “FXTAS: An Older Face of the Fragile X Gene”

Hagerman is a molecular geneticist with a principal interest in understanding the basis for neurodevelopmental and neurodegenerative diseases. In particular, the Hagerman lab has made a number of important observations related to the mechanism of gene expression of the fragile X (FMR1) gene. Mutations of the FMR1 gene give rise to fragile X syndrome, the leading heritable form of mental impairment and autism.