Morse Scholar Alumni 2022–2023
Current Position
Associate Physical Scientist
The Rand Corporation
Contact
About
His research is focused on using human pluripotent stem cells (trisomy 21 iPSCs) to study different aspects of cortical development and aging in Down Syndrome (DS) including interneuron development and the effects of oxidative stress on neuron function. He specifically studies a subset of neurons, Basal Forebrain Cholinergic Neurons, which are known to degenerate in patients with Alzheimer’s Disease (AD) and DS-AD patients. The results from this study will help us find the link between the early onset of AD in the DS population, as well as offer a broad understanding of BFCN pathology in AD.
Education
| 2014 | BS | Biochemistry and Molecular Biology | University of California Santa Cruz |
| 2021 | MA | MPA – Public Affairs | University of Wisconsin |
| 2022 | MS | Cellular and Molecular Biology | University of Wisconsin |
| 2024 | PhD | Cell/Cellular and Molecular Biology | University of Wisconsin |
| 2022–2023 | Morse Scholar | Major Professor: Anita Bhattacharyya, PhD | Waisman Center, University of Wisconsin-Madison |
| 2022–2023 | Fellow | Ciencia Academy | Yale |
In the News
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Jose Martinez connects science and policy as a BTP trainee
March 7, 2022 - Student Spotlight: Jose Martinez
July 24, 2019
Research Links
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https://www.linkedin.com/in/jolumart/ |
Selected Publications
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Martinez, J. L., Piciw, J. G., Crockett, M., Sorci, I. A., Makwana, N., Sirois, C. L., Giffin-Rao, Y., & Bhattacharyya, A. (2024). Transcriptional consequences of trisomy 21 on neural induction. Frontiers in cellular neuroscience, 18, 1341141. https://doi.org/10.3389/fncel.2024.1341141
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Baxi, S., Cabreros, I., Meredith, L. S., Holliday, S. B., Martinez, J., & Piquado, T. (2023). US Military Healthcare Professionals’ Practice, Knowledge, and Misconceptions About Concussion. The Journal of head trauma rehabilitation, 38(5), 391–400. https://doi.org/10.1097/HTR.0000000000000828
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Martinez, J. L., Zammit, M. D., West, N. R., Christian, B. T., & Bhattacharyya, A. (2021). Corrigendum: Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease. Frontiers in aging neuroscience, 13, 742233. https://doi.org/10.3389/fnagi.2021.742233
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Martinez, J. L., Zammit, M. D., West, N. R., Christian, B. T., & Bhattacharyya, A. (2021). Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease. Frontiers in aging neuroscience, 13, 703876. https://doi.org/10.3389/fnagi.2021.703876