Luigi Puglielli, MD, PhD – Slide of the Week
The aberrant accumulation of toxic protein aggregates is a key feature of many neurodegenerative diseases, including Huntington’s disease, amyotrophic lateral sclerosis and Alzheimer’s disease. As such, improving normal proteostatic mechanisms is an active target for biomedical research.
April 23, 2018
Denise Ney, PhD – Slide of the Week
Individuals with phenylketonuria (PKU) have a risk of cognitive impairment and inflammation. Many follow a low-phenylalanine (low-Phe) diet devoid of animal protein in combination with medical foods (MFs).
April 15, 2018
Albee Messing, VMD, PhD – Slide of the Week
Title: Elimination of GFAP from the Central Nervous System (CNS) in Mouse Models of Alexander Disease Legend: A single injection of antisense oligonucleotides into the lateral ventricle of adult mice leads to nearly complete elimination of …
April 8, 2018
Janet Lainhart, PhD – Slide of the Week
The thalamus is a key sensorimotor relay area that is implicated in autism spectrum disorder (ASD). However, it is unknown how the thalamus and white-matter structures that contain thalamo-cortical fiber connections (e.g., the internal capsule) develop from childhood into adulthood and whether this microstructure relates to basic motor challenges in ASD.
April 2, 2018
Marsha R. Mailick, PhD – Slide of the Week
The FMR1 premutation is of increasing interest to the fragile X syndrome (FXS) community, as questions about a primary premutation phenotype warrant research attention. One hundred FMR1 premutation carrier mothers (mean age = 58; 67 to 138 CGG repeats) of adults with fragile X syndrome were studied with respect to their physical and mental health, and motor and neurocognitive characteristics.
March 19, 2018
Ruth Litovsky, PhD – Slide of the Week
Many people with single-sided deafness have tinnitus in the deaf ear (and normal hearing in the other ear). We are conducting a clinical trial in collaboration with surgeons at Harvard Medical School, to determine if a CI in the deaf ear provides: (A) relief from tinnitus due to the electrical stimulation, and (B) improved ability to localize sounds.
March 11, 2018
James Li, PhD – Slide of the Week
Inconsistent parental discipline is a robust correlate of child attention-deficit/hyperactivity disorder (ADHD) symptoms, but few studies have considered the role of inconsistent positive parenting on ADHD, as well as the effects of stress on negative and positive parental consistency.
March 4, 2018
Margarita Kaushanskaya, PhD – Slide of the Week
This study tested the effect of Spanish-accented speech on sentence comprehension in children with different degrees of Spanish experience. The hypothesis was that earlier acquisition of Spanish would be associated with enhanced comprehension of Spanish-accented speech.
February 26, 2018
Katherine C. Hustad, PhD – Slide of the Week
Although children with cerebral palsy (CP) are at an increased risk for developing speech, language, and executive function (EF) impairments, little is known regarding the relationship among these risk factors.
February 18, 2018
Edward Hubbard, PhD – Slide of the Week
One of the key ways that we make sense of numbers is by creating a “mental number line”. Previous research with whole numbers has demonstrated that (at least in Western cultures) small numbers are thought of as being on the left side of space, and large numbers on the right.
February 11, 2018- More Slide of the Week posts
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