Xinyu Zhao, PhD – Slide of the Week
Adult neural stem cells in mouse models of fragile X syndrome (FXS) have elevated histone acetylation, leading to reduced neurogenesis. Treatment with either Nutlin-3 or Curcumin rebalances histone acetylation and rescues cognitive functions
August 10, 2018
Houri K. Vorperian, PhD – Slide of the Week
A single-word identification test was used to study speech production in children and adults with Down syndrome (DS) to determine the developmental pattern of speech intelligibility with an emphasis on vowels.
August 5, 2018
Brittany G. Travers, PhD – Slide of the Week
The current study investigated the relation between postural balance and performance of daily living skills (DLS) in youth with autism spectrum disorder (ASD). Fifty-two youth with ASD (6–17 years; IQ ≥ 67) completed standardized balance testing and parent-reported DLS measures.
July 29, 2018
Ender Tekin, PhD – Slide of the Week
Children who cannot effectively read print because of a visual, physical, perceptual, developmental, cognitive or learning disability, are considered to have a print disability.
July 22, 2018
John Svaren, PhD – Slide of the Week
Our goal was to define the genetic cause of the profound hypomyelination in the taiep rat model and determine its relevance to human white matter disease.
July 15, 2018
Masatoshi Suzuki, DVM, PhD – Slide of the Week
Human induced-pluripotent stem cells are a promising resource for propagation of myogenic progenitors. Our group recently reported a unique protocol for the derivation of myogenic progenitors directly (without genetic modification) from human pluripotent cells using free-floating spherical culture.
July 9, 2018
Audra Sterling, PhD – Slide of the Week
This study compared gesture use in young children with DS and TD as well as how mothers respond to child gestures based on child age and diagnosis.
June 24, 2018
Kristin Shutts, PhD – Slide of the Week
How does social information affect the perception of taste early in life? Does mere knowledge of other people’s food preferences impact children’s own experience when eating? In Experiment 1, 5- and 6- year- old children consumed more of a food described as popular with other children than a food that was described as unpopular with other children, even though the two foods were identical.
June 17, 2018
Lawrence D. Shriberg, PhD – Slide of the Week
Genetic investigations of people with impaired development of spoken language provide windows into key aspects of human biology. Over 15 years after FOXP2 was identified, most speech and language impairments remain unexplained at the molecular level.
June 10, 2018
Krishanu Saha, PhD – Slide of the Week
We present and characterize a robust method for rapid, scarless introduction or correction of disease-associated variants in hPSCs using CRISPR/Cas9. Utilizing non-integrated plasmid vectors that express a puromycin N-acetyl-transferase (PAC) gene, whose expression and translation is linked to that of Cas9, we transiently select for cells based on their early levels of Cas9 protein.
June 3, 2018- More Slide of the Week posts
Dedicated to advancing knowledge about human development, developmental disabilities, and neurodegenerative diseases