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University of Wisconsin–Madison
Waisman Center
Waisman Center
Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
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  1. Home
  2. Down Syndrome

Down Syndrome

Basal Forebrain Cholinergic Neurons: Linking Down Syndrome and Alzheimer’s Disease

Neurofibrillary tau depositions emerge with subthreshold cerebral beta-amyloidosis in down syndrome

DSCAM/PAK1 pathway suppression reverses neurogenesis deficits in iPSC-derived cerebral organoids from patients with Down syndrome

Opportunities, barriers, and recommendations in down syndrome research

White matter microstructure associations with episodic memory in adults with Down syndrome: a tract-based spatial statistics study

Spoken language outcome measures for treatment studies in Down syndrome: feasibility, practice effects, test-retest reliability, and construct validity of variables generated from expressive language sampling

PET measurement of longitudinal amyloid load identifies the earliest stages of amyloid-beta accumulation during Alzheimer’s disease progression in Down syndrome

Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer’s Disease Dementia and Mild Cognitive Impairment in Adults with Down Syndrome

Patterns of glucose hypometabolism in Down syndrome resemble sporadic Alzheimer’s disease except for the putamen

Cognitive indicators of transition to preclinical and prodromal stages of Alzheimer’s disease in Down syndrome

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