Bernadette Gillick, PhD, MSPT, PT
Position title: Professor, Pediatrics, and Developmental Pediatrics & Rehabilitation Medicine
Contact Information
Waisman Center
1500 Highland Ave
Room 491
Madison, WI 53706
bgillick@wisc.edu
Pediatric Neuromodulation Laboratory
Research Statement
Dr. Gillick’s research is dedicated to investigating cortical plasticity and recovery from neurologic insult in both adult and pediatric populations. Her research encompasses the use of non-invasive brain stimulation, in combination with behavioral training, for improved motor function. Current grants support investigation of the use of non-invasive brain stimulation with and without the combination of constraint-induced therapy in children with stroke and resultant hemiparesis. Neuroimaging and neuronavigation allows advanced understanding of the reorganization and structure of the brain which survived the stroke, and the influence of interventions on neurorecovery.
Selected Publications
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Sutter, E. N., Legare, J. M., Villegas, M. A., Collins, K. M., Eickhoff, J., & Gillick, B. T. (2024). Evidence-Based Infant Assessment for Cerebral Palsy: Diagnosis Timelines and Intervention Access in a Newborn Follow-up Setting. Journal of child neurology, 39(13-14), 461–469. https://doi.org/10.1177/08830738241279690
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Sutter, E. N., Casey, C. P., & Gillick, B. T. (2024). Single-pulse transcranial magnetic stimulation for assessment of motor development in infants with early brain injury. Expert review of medical devices, 1–8. Advance online publication. https://doi.org/10.1080/17434440.2023.2299310
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Christopher, P., Sutter, E. N., Gavioli, M., Lench, D. H., Nytes, G., Mak, V., Simpson, E. A., Ikonomidou, C., Villegas, M. A., Saiote, C., & Gillick, B. T. (2023). Safety, tolerability and feasibility of remotely-instructed home-based transcranial direct current stimulation in children with cerebral palsy. Brain stimulation, 16(5), 1325–1327. Advance online publication. https://doi.org/10.1016/j.brs.2023.08.024
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Saiote, C., Sutter, E., Xenopoulos-Oddsson, A., Rao, R., Georgieff, M., Rudser, K., Peyton, C., Dean, D., McAdams, R. M., & Gillick, B. (2022). Study Protocol: Multimodal Longitudinal Assessment of Infant Brain Organization and Recovery in Perinatal Brain Injury. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association, 34(2), 268–276. https://doi.org/10.1097/PEP.0000000000000886
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Sutter, E. N., Francis, L. S., Francis, S. M., Lench, D. H., Nemanich, S. T., Krach, L. E., Sukal-Moulton, T., & Gillick, B. T. (2021). Disrupted Access to Therapies and Impact on Well-Being During the COVID-19 Pandemic for Children With Motor Impairment and Their Caregivers. American journal of physical medicine & rehabilitation, 100(9), 821–830. https://doi.org/10.1097/PHM.0000000000001818
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Chantigian, D. P., Larson, M., Chen, M., Gillick, B. T., Cross, T. J., & Keller-Ross, M. L. (2021). Heart rate and blood pressure responses to corticomotor stimulation in young, healthy adults. Clinical neurophysiology practice, 6, 206–208. https://doi.org/10.1016/j.cnp.2021.06.004
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Mantell, K. E., Sutter, E. N., Shirinpour, S., Nemanich, S. T., Lench, D. H., Gillick, B. T., & Opitz, A. (2021). Evaluating transcranial magnetic stimulation (TMS) induced electric fields in pediatric stroke. NeuroImage. Clinical, 29, 102563. https://doi.org/10.1016/j.nicl.2021.102563
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O’Leary, G. H., Jenkins, D. D., Coker-Bolt, P., George, M. S., Kautz, S., Bikson, M., Gillick, B. T., & Badran, B. W. (2021). From adults to pediatrics: A review noninvasive brain stimulation (NIBS) to facilitate recovery from brain injury. Progress in brain research, 264, 287–322. https://doi.org/10.1016/bs.pbr.2021.01.019
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Keller-Ross, M. L., Chantigian, D. P., Nemanich, S., & Gillick, B. T. (2021). Cardiovascular Effects of Transcranial Direct Current Stimulation and Bimanual Training in Children With Cerebral Palsy. Pediatric physical therapy : the official publication of the Section on Pediatrics of the American Physical Therapy Association, 33(1), 11–16. https://doi.org/10.1097/PEP.0000000000000762
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Behan, M., Nawshin, T., Nemanich, S., Kowalski, J., Sutter, E., Francis, S., Dubinsky, J., Freese, R., Rudser, K., & Gillick, B. (2020). A crossed-disciplinary evaluation of parental perceptions surrounding pediatric non-invasive brain stimulation research. International journal of pharmaceutical and healthcare marketing, 14(4), 623–640. https://doi.org/10.1108/ijphm-01-2020-0005
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Lench, D. H., Simpson, E., Sutter, E. N., & Gillick, B. T. (2020). Feasibility of remote transcranial direct current stimulation for pediatric cerebral palsy during the COVID-19 pandemic. Brain stimulation, 13(6), 1803–1804. https://doi.org/10.1016/j.brs.2020.10.010
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Bikson, M., Hanlon, C. A., Woods, A. J., Gillick, B. T., Charvet, L., Lamm, C., Madeo, G., Holczer, A., Almeida, J., Antal, A., Ay, M. R., Baeken, C., Blumberger, D. M., Campanella, S., Camprodon, J. A., Christiansen, L., Loo, C., Crinion, J. T., Fitzgerald, P., Gallimberti, L., … Ekhtiari, H. (2020). Guidelines for TMS/tES clinical services and research through the COVID-19 pandemic. Brain stimulation, 13(4), 1124–1149. https://doi.org/10.1016/j.brs.2020.05.010
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Francis, S. M., Beard, K. L., Tseng, A., Chen, M., Gillick, B. T., Jacob, S., & Conelea, C. A. (2020). Transcranial direct current stimulation for compulsivity in adolescent fraternal twins with neurodevelopmental disorders. Brain stimulation, 13(4), 1153–1155. https://doi.org/10.1016/j.brs.2020.05.007
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Kowalski, J. L., Hickey, M., Rao, R., Georgieff, M. K., Chen, M., & Gillick, B. T. (2020). Safety of single-pulse TMS in two infants with implanted patent ductus arteriosus closure devices. Brain stimulation, 13(3), 861–862. https://doi.org/10.1016/j.brs.2020.03.007
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Rich, T. L., Nemanich, S., Chen, C. Y., Sutter, E. N., Feyma, T., Krach, L. E., & Gillick, B. T. (2020). Ipsilateral Corticospinal Tract Excitability Contributes to the Severity of Mirror Movements in Unilateral Cerebral Palsy: A Case Series. Clinical EEG and neuroscience, 51(3), 185–190. https://doi.org/10.1177/1550059419899323
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Legon, W., Adams, S., Bansal, P., Patel, P. D., Hobbs, L., Ai, L., Mueller, J. K., Meekins, G., & Gillick, B. T. (2020). A retrospective qualitative report of symptoms and safety from transcranial focused ultrasound for neuromodulation in humans. Scientific reports, 10(1), 5573. https://doi.org/10.1038/s41598-020-62265-8
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Nemanich, S. T., Mueller, B. A., & Gillick, B. T. (2019). Neurite orientation dispersion and density imaging quantifies corticospinal tract microstructural organization in children with unilateral cerebral palsy. Human brain mapping, 40(17), 4888–4900. https://doi.org/10.1002/hbm.24744
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Gröhn, H., Gillick, B. T., Tkáč, I., Bednařík, P., Mascali, D., Deelchand, D. K., Michaeli, S., Meekins, G. D., Leffler-McCabe, M. J., MacKinnon, C. D., Eberly, L. E., & Mangia, S. (2019). Influence of Repetitive Transcranial Magnetic Stimulation on Human Neurochemistry and Functional Connectivity: A Pilot MRI/MRS Study at 7 T. Frontiers in neuroscience, 13, 1260. https://doi.org/10.3389/fnins.2019.01260
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Nemanich, S. T., Rich, T. L., Gordon, A. M., Friel, K. M., & Gillick, B. T. (2019). Bimanual Skill Learning after Transcranial Direct Current Stimulation in Children with Unilateral Cerebral Palsy: A Brief Report. Developmental neurorehabilitation, 22(7), 504–508. https://doi.org/10.1080/17518423.2019.1600065
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Kowalski, J. L., Nemanich, S. T., Nawshin, T., Chen, M., Peyton, C., Zorn, E., Hickey, M., Rao, R., Georgieff, M., Rudser, K., & Gillick, B. T. (2019). Motor Evoked Potentials as Potential Biomarkers of Early Atypical Corticospinal Tract Development in Infants with Perinatal Stroke. Journal of clinical medicine, 8(8), 1208. https://doi.org/10.3390/jcm8081208
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Nemanich, S. T., Chen, C. Y., Chen, M., Zorn, E., Mueller, B., Peyton, C., Elison, J. T., Stinear, J., Rao, R., Georgieff, M., Menk, J., Rudser, K., & Gillick, B. (2019). Safety and Feasibility of Transcranial Magnetic Stimulation as an Exploratory Assessment of Corticospinal Connectivity in Infants After Perinatal Brain Injury: An Observational Study. Physical therapy, 99(6), 689–700. https://doi.org/10.1093/ptj/pzz028
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Nemanich, S. T., Rich, T. L., Chen, C. Y., Menk, J., Rudser, K., Chen, M., Meekins, G., & Gillick, B. T. (2019). Influence of Combined Transcranial Direct Current Stimulation and Motor Training on Corticospinal Excitability in Children With Unilateral Cerebral Palsy. Frontiers in human neuroscience, 13, 137. https://doi.org/10.3389/fnhum.2019.00137
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Rich, T. L., & Gillick, B. T. (2019). Electrode Placement in Transcranial Direct Current Stimulation-How Reliable Is the Determination of C3/C4?. Brain sciences, 9(3), 69. https://doi.org/10.3390/brainsci9030069