H. Hill Goldsmith, PhD
Position title: Antoine Bascom Professor & Leona Tyler Professor of Psychology
PhD, University of Minnesota
Contact Information
Waisman Center
1500 Highland Ave
Room 573
Madison, WI 53706
608.265.2674
hill.goldsmith@wisc.edu
Lab Website: Wisconsin Twin Research
Research Statement
Our research focus is temperament and the role of temperament in developmental risk and resilience. We consider broad themes of affective development, psychological adjustment, genetics, brain development, and family context. See our lab website for more details. Please visit the Wisconsin Twin Research website for more details.
Selected Publications
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Planalp, E. M., Dowe, K. N., Alexander, A. L., Goldsmith, H. H., Davidson, R. J., & Dean, D. C., 3rd (2023). White matter microstructure predicts individual differences in infant fear (But not anger and sadness). Developmental Science, 26(3), e13340. https://doi.org/10.1111/desc.13340
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Birn, R. M., Dean, D. C., 3rd, Wooten, W., Planalp, E. M., Kecskemeti, S., Alexander, A. L., Goldsmith, H. H., & Davidson, R. J. (2022). Reduction of motion artifacts in functional connectivity resulting from infrequent large motion. Brain Connectivity, 12(8), 740–753. https://doi.org/10.1089/brain.2021.0133
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Goldsmith, H. H., Hilton, E. C., Phan, J. M., Sarkisian, K. L., Carroll, I. C., Lemery-Chalfant, K., & Planalp, E. M. (2022). Childhood inhibition predicts adolescent social anxiety: Findings from a longitudinal twin study. Development and psychopathology, 1–20. https://doi.org/10.1017/S0954579422000864
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Bas-Hoogendam, J. M., Bernstein, R., Benson, B. E., Buss, K. A., Gunther, K. E., Pérez-Edgar, K., Salum, G. A., Jackowski, A. P., Bressan, R. A., Zugman, A., Degnan, K. A., Filippi, C. A., Fox, N. A., Henderson, H. A., Tang, A., Zeytinoglu, S., Harrewijn, A., Hillegers, M., White, T., van IJzendoorn, M. H., … ENIGMA-Anxiety Working Group (2022). Structural brain correlates of childhood inhibited temperament: An ENIGMA-anxiety mega-analysis. Journal of the American Academy of Child and Adolescent Psychiatry, 61(9), 1182–1188. https://doi.org/10.1016/j.jaac.2022.04.023
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Sarkisian, K., Planalp, E., Van Hulle, C., & Goldsmith, H. H. (2022). Leveraging latent profile analysis to synthesize childhood and adolescent risk factors for suicidal ideation. PloS one, 17(8), e0272400. https://doi.org/10.1371/journal.pone.0272400
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Moore, M. N., Planalp, E. M., Van Hulle, C. A., & Goldsmith, H. H. (2022). Pediatric assessment of Research Domain Criteria positive and negative valence systems: Partial genetic mediation of links to problem behaviors. Journal of Psychopathology and Clinical Science, 131(6), 626–640. https://doi.org/10.1037/abn0000652
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Luo, Z., Adluru, N., Dean, D. C., 3rd, Alexander, A. L., & Goldsmith, H. H. (2022). Genetic and environmental influences of variation in diffusion MRI measures of white matter microstructure. Brain structure & function, 227(1), 131–144. https://doi.org/10.1007/s00429-021-02393-7
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Oro, V., Goldsmith, H. H., & Lemery-Chalfant, K. (2021). Elucidating the Links Between Mother and Father Alcohol Use Disorder and Adolescent Externalizing Psychopathology: A Test of Transmission Specificity Within Competing Factor Structures and Genetic and Environmental Liabilities. Behavior genetics, 51(5), 512–527. https://doi.org/10.1007/s10519-021-10072-w
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Dean, D. C., 3rd, Madrid, A., Planalp, E. M., Moody, J. F., Papale, L. A., Knobel, K. M., Wood, E. K., McAdams, R. M., Coe, C. L., Hill Goldsmith, H., Davidson, R. J., Alisch, R. S., & Kling, P. J. (2021). Cord blood DNA methylation modifications in infants are associated with white matter microstructure in the context of prenatal maternal depression and anxiety. Scientific reports, 11(1), 12181. https://doi.org/10.1038/s41598-021-91642-0
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Phan, J. M., Van Hulle, C. A., Shirtcliff, E. A., Schmidt, N. L., & Goldsmith, H. H. (2021). Longitudinal effects of family psychopathology and stress on pubertal maturation and hormone coupling in adolescent twins. Developmental psychobiology, 63(3), 512–528. https://doi.org/10.1002/dev.22028
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Sarkisian, K., Van Hulle, C., & Goldsmith, H. H. (2021). Persistence During Childhood Problem-Solving as a Predictor of Active Suicidal Ideation During Adolescence. Research on child and adolescent psychopathology, 49(4), 533–543. https://doi.org/10.1007/s10802-020-00726-4
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Dowe, K. N., Planalp, E. M., Dean, D. C., 3rd, Alexander, A. L., Davidson, R. J., & Goldsmith, H. H. (2020). Early microstructure of white matter associated with infant attention. Developmental cognitive neuroscience, 45, 100815. https://doi.org/10.1016/j.dcn.2020.100815
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Schmidt, N., Lemery-Chalfant, K., & Goldsmith, H. (n.d.). Wisconsin Twin Project Overview: Temperament and Affective Neuroscience. Twin Research and Human Genetics, 1-6. doi:10.1017/thg.2019.108
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Guerrero JM, Adluru N, Bendlin BB, Goldsmith HH, Schaefer SM, Davidson RJ, Kecskemeti SR, Zhang H, Alexander AL. (2019). Optimizing the intrinsic parallel diffusivity in NODDI: An extensive empirical evaluation. PLoS One. 14(9):e0217118. doi: 10.1371/journal.pone.0217118.
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Planalp EM, Van Hulle CA, Goldsmith HH. (2019). Parenting in context: Marital adjustment, parent affect, and child temperament in complex families. Journal of Family Psychology, 33(5):532-541. doi: 10.1037/fam0000511.
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Carroll IC, Planalp EM, Van Hulle CA, Goldsmith HH. (2019). Peer Victimization and Selective Attention in Adolescence: Evidence from a Monozygotic Twin Difference Design. Journal of Abnormal Child Psychology, 47(8):1303-1313. doi: 10.1007/s10802-019-00516-7.
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Adluru N, Luo Z, Van Hulle CA, Schoen AJ, Davidson RJ, Alexander AL, Goldsmith HH. (2019). Anxiety-related experience-dependent white matter structural differences in adolescence: A monozygotic twin difference approach. Science Reports, 18;7(1):8749. PMID: 28821748. PMCID: PMC5562810. DOI: 10.1038/s41598-017-08107-6
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Planalp, E. M., & Goldsmith, H. H. (2019). Observed Profiles of Infant Temperament: Stability, Heritability, and Associations With Parenting. Child Development. In Press. 2019 Jul 4. doi: 10.1111/cdev.13277.
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Sarkisian KL, Van Hulle CA, Hill Goldsmith H. (2019). Brooding, Inattention, and Impulsivity as Predictors of Adolescent Suicidal Ideation. Journal of Abnormal Child Psychology, 47(2):333-344. PMID: 29808397. PMCID: PMC6265119. doi: 10.1007/s10802-018-0435-5.
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Dean DC 3rd, Planalp EM, Wooten W, Kecskemeti SR, Adluru N, Schmidt CK, Frye C, Birn RM, Burghy CA, Schmidt NL, Styner MA, Short SJ, Kalin NH, Goldsmith HH, Alexander AL, Davidson RJ. (2019). Association of Prenatal Maternal Depression and Anxiety Symptoms With Infant White Matter Microstructure. JAMA Pediatrics, 172(10):973-981. PMID: 30177999. PMCID: PMC6190835. DOI: 10.1001/jamapediatrics.2018.2132
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Van Hulle CA, Lemery-Chalfant K, Hill Goldsmith H. (2018) Parent-Offspring Transmission of Internalizing and Sensory over-Responsivity Symptoms in Adolescence. Journal of Abnormal Child Psychology, 46(3):557-567. doi: 10.1007/s10802-017-0300-y.
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Dean DC 3rd, Planalp EM, Wooten W, Schmidt CK, Kecskemeti SR, Frye C, Schmidt NL, Goldsmith HH, Alexander AL, Davidson RJ. (2018). Investigation of brain structure in the 1-month infant. Brain Structure and Function, 223(4):1953-1970. doi: 10.1007/s00429-017-1600-2.
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Alisch RS, Van Hulle C, Chopra P, Bhattacharyya A, Zhang SC, Davidson RJ, Kalin NH, Goldsmith HH. (2017). A multi-dimensional characterization of anxiety in monozygotic twin pairs reveals susceptibility loci in humans. Translational Psychiatry, 7(12):1282. PMCID: PMC5802687. DOI: 10.1038/s41398-017-0047-9
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Van Hulle CA, Clifford S, Moore MN, Lemery-Chalfant K, Goldsmith HH. (2017) Partial replication of two rumination-related candidate gene studies. Cognition & Emotion. 31(5):963-971. doi: 10.1080/02699931.2016.1168779.
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Planalp EM, Van Hulle C, Lemery-Chalfant K, Goldsmith HH. (2017) Genetic and Environmental Contributions to the Development of Positive Affect in Infancy. Emotion, 17(3):412-420. PMID: 27797564. PMCID: PMC5367954. doi: 10.1037/emo0000238.
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Van Hulle CA, Moore MN, Lemery-Chalfant K, Goldsmith HH, Brooker RJ. (2017) Infant stranger fear trajectories predict anxious behaviors and diurnal cortisol rhythm during childhood. Development and Psychopathology, 29(3):1119-1130. PMCID: PMC5431083. doi: 10.1017/S0954579417000311.
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Lundwall RA, Dannemiller JL, Goldsmith HH. (2017) Genetic associations with reflexive visual attention in infancy and childhood. Developmental Science. 20(3). doi: 10.1111/desc.12371.
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Planalp EM, Van Hulle C, Gagne JR, Goldsmith HH. (2017) The Infant Version of the Laboratory Temperament Assessment Battery (Lab-TAB): Measurement Properties and Implications for Concepts of Temperament. Frontiers in Psychology. 24;8:846. doi: 10.3389/fpsyg.2017.00846.
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Gagne JR, O’Sullivan DL, Schmidt NL, Spann CA, Goldsmith HH. (2017) The Shared Etiology of Attentional Control and Anxiety: An Adolescent Twin Study. Journal of Research on Adolescence, 27(1):122-138. PMID: 28498525. PMCID: PMC5431083. doi: 10.1111/jora.12260.
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Brooker RJ, Canen MJ, Davidson RJ, Hill Goldsmith H. (2017). Short- and long-term stability of alpha asymmetry in infants: Baseline and affective measures. Psychophysiology, 54(8):1100-1109. doi: 10.1111/psyp.12866.
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Scott BG, Lemery-Chalfant K, Clifford S, Tein JY, Stoll R, Goldsmith HH. (2016) A Twin Factor Mixture Modeling Approach to Childhood Temperament: Differential Heritability. Child Development. 87(6):1940-1955. doi: 10.1111/cdev.12561.
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Burghy CA, Fox ME, Cornejo MD, Stodola DE, Sommerfeldt SL, Westbrook CA, Van Hulle C, Schmidt NL, Goldsmith HH, Davidson RJ, Birn RM. (2016). Experience-Driven Differences in Childhood Cortisol Predict Affect-Relevant Brain Function and Coping in Adolescent Monozygotic Twins. Science Reports, 6:37081. doi: 10.1038/srep37081.
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Sarkisian K, Van Hulle C, Lemery-Chalfant K, Goldsmith HH. (2016) Childhood inhibitory control and adolescent impulsivity and novelty seeking as differential predictors of relational and overt aggression. Journal of Research in Personality. 67:144-150. doi:10.1016/j.jrp.2016.07.011.
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Brooker RJ, Davidson RJ, Goldsmith HH. (2016) Maternal negative affect during infancy is linked to disrupted patterns of diurnal cortisol and alpha asymmetry across contexts during childhood. Journal of Experimental Child Psychology. 142:274-90. doi: 10.1016/j.jecp.2015.08.011.
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Brooker RJ, Phelps RA, Davidson RJ, Goldsmith HH. (2016) Context differences in delta beta coupling are associated with neuroendocrine reactivity in infants. Developmental Psychobiology. 58(3):406-18. doi: 10.1002/dev.21381.
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Van Hulle C, Lemery-Chalfant K, Goldsmith HH. (2015) Trajectories of Sensory Over-Responsivity from Early to Middle Childhood: Birth and Temperament Risk Factors. PLoS One. 24;10(6):e0129968. doi: 10.1371/journal.pone.0129968.
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Clifford S, Lemery-Chalfant K, Goldsmith HH. (2015) The Unique and Shared Genetic and Environmental Contributions to Fear, Anger, and Sadness in Childhood. Child Development. 86(5):1538-56. doi: 10.1111/cdev.12394.
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Eggum-Wilkens ND, Lemery-Chalfant K, Aksan N, Goldsmith HH. (2015) Self-Conscious Shyness: Growth during Toddlerhood, Strong Role of Genetics, and No Prediction from Fearful Shyness. Infancy. 20(2):160-188.
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Van Hulle CA, Moore MN, Shirtcliff EA, Lemery-Chalfant K, Goldsmith HH. (2015) Genetic and Environmental Contributions to Covariation Between DHEA and Testosterone in Adolescent Twins. Behavioral Genetics. 45(3):324-40. doi: 10.1007/s10519-015-9709-7.
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Vendlinski MK, Javaras KN, Van Hulle CA, Lemery-Chalfant K, Maier R, Davidson RJ, Goldsmith HH. (2014) Relative influence of genetics and shared environment on child mental health symptoms depends on comorbidity. PLoS One. 31;9(7):e103080.
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Brooker RJ, Buss KA, Lemery-Chalfant K, Aksan N, Davidson RJ, Goldsmith HH. (2014) Profiles of observed infant anger predict preschool behavior problems: Moderation by life stress. Developmental Psychology. 50(10):2343-52.
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Moore MN, Salk RH, Van Hulle CA, Abramson LY, Hyde JS, Lemery-Chalfant K, Goldsmith HH. (2013) Genetic and Environmental Influences on Rumination, Distraction, and Depressed Mood in Adolescence. Clinical Psychological Science. Jul 1;1(3):316-322.
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Lemery-Chalfant K, Kao K, Swann G, Goldsmith HH. (2013) Childhood temperament: passive gene-environment correlation, gene-environment interaction, and the hidden importance of the family environment. Development and Psychopathology. Feb;25(1):51-63.
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Gagne JR, Miller MM, Goldsmith HH. (2013) Early-but modest-gender differences in focal aspects of childhood temperament. Personality and Individual Differences. 55(2):95-100.
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Schmidt NL, Van Hulle CA, Brooker RJ, Meyer LR, Lemery-Chalfant K, Goldsmith HH. (2013) Wisconsin Twin Research: early development, childhood psychopathology, autism, and sensory over-responsivity. Twin Research and Human Genetics. Feb;16(1):376-84
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Brooker RJ, Buss KA, Lemery-Chalfant K, Aksan N, Davidson RJ, & Goldsmith HH. (2013) The development of stranger fear in infancy and toddlerhood: Normative development, individual differences, antecedents, and outcomes. Developmental Science. 16(6):864-78.
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Van Hulle CA, Schmidt NL, Goldsmith HH. (2012) Is sensory over-responsivity distinguishable from childhood behavior problems? A phenotypic and genetic analysis. The Journal of Child Psychology and Psychiatry. Jan;53(1):64-72.
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Van Hulle CA, Shirtcliff EA, Lemery-Chalfant K, Goldsmith HH. (2012) Genetic and environmental influences on individual differences in cortisol level and circadian rhythm in middle childhood. Hormones and Behavior. Horm Behav. 2012 Jun;62(1):36-42.
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Gagne JR, Goldsmith HH. (2011) A longitudinal analysis of anger and inhibitory control in twins from 12 to 36 months of age. Developmental Science. Jan;14(1):112-24.
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Gagne JR, Van Hulle CA, Aksan N, Essex MJ, Goldsmith HH. (2011) Deriving childhood temperament measures from emotion-eliciting behavioral episodes: scale construction and initial validation. Psychological Assessment. Jun;23(2):337-53.
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Keuler MM, Schmidt NL, Van Hulle CA, Lemery-Chalfant K, Goldsmith HH. (2011) Sensory overresponsivity: prenatal risk factors and temperamental contributions. Journal of Developmental & Behavioral Pediatrics. Sep;32(7):533-41.
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Volbrecht MM, Goldsmith HH. (2010) Early temperamental and family predictors of shyness and anxiety. Developmental Psychology. Sep;46(5):1192-205.