Johnson, PhD, Sterling C.

Rea Reyes, R. E., Cody, K. A., Wilson, R. E., Zetterberg, H., Chin, N. A., Jonaitis, E. M., Bahr, M., Mandel, O., Wintlend, M., Bendlin, B. B., Okonkwo, O. C., Clark, L. R., Zammit, M., Asthana, S., Christian, B. T., Betthauser, T. J., Eisenmenger, L., Langhough, R. E., & Johnson, S. C. (2024). Visual read of [F-18]florquinitau PET that includes and extends beyond the mesial temporal lobe is associated with increased plasma pTau217 and cognitive decline in a cohort that is enriched with risk for Alzheimer’s disease. Alzheimer’s & dementia : the journal of the Alzheimer’s Association, 10.1002/alz.14406. Advance online publication. https://doi.org/10.1002/alz.14406

Jonaitis, E. M., Hermann, B. P., Mueller, K. D., Clark, L. R., Du, L., Betthauser, T. J., Cody, K., Gleason, C. E., Christian, B. T., Asthana, S., Chappell, R. J., Chin, N. A., Johnson, S. C., & Langhough, R. E. (2024). Longitudinal normative standards for cognitive tests and composites using harmonized data from two Wisconsin AD-risk-enriched cohorts. Alzheimer’s & dementia, 20(5), 3305–3321. https://doi.org/10.1002/alz.13774

Zammit, M. D., Betthauser, T. J., McVea, A. K., Laymon, C. M., Tudorascu, D. L., Johnson, S. C., Hartley, S. L., Converse, A. K., Minhas, D. S., Zaman, S. H., Ances, B. M., Stone, C. K., Mathis, C. A., Cohen, A. D., Klunk, W. E., Handen, B. L., Christian, B. T., & Alzheimer’s Biomarker Consortium – Down Syndrome (2024). Characterizing the emergence of amyloid and tau burden in Down syndrome. Alzheimer’s & dementia, 20(1), 388–398. https://doi.org/10.1002/alz.13444

Moody, J. F., Dean, D. C., 3rd, Kecskemeti, S. R., Blennow, K., Zetterberg, H., Kollmorgen, G., Suridjan, I., Wild, N., Carlsson, C. M., Johnson, S. C., Alexander, A. L., & Bendlin, B. B. (2022). Associations between diffusion MRI microstructure and cerebrospinal fluid markers of Alzheimer’s disease pathology and neurodegeneration along the Alzheimer’s disease continuum. Alzheimer’s & dementia (Amsterdam, Netherlands), 14(1), e12381. https://doi.org/10.1002/dad2.12381

Betthauser, T. J., Bilgel, M., Koscik, R. L., Jedynak, B. M., An, Y., Kellett, K. A., Moghekar, A., Jonaitis, E. M., Stone, C. K., Engelman, C. D., Asthana, S., Christian, B. T., Wong, D. F., Albert, M., Resnick, S. M., Johnson, S. C., & Alzheimer’s Disease Neuroimaging Initiative (2022). Multi-method investigation of factors influencing amyloid onset and impairment in three cohorts. Brain : a journal of neurology, 145(11), 4065–4079. https://doi.org/10.1093/brain/awac213

Bazydlo, A. M., Zammit, M. D., Wu, M., Lao, P. J., Dean, D. C., 3rd, Johnson, S. C., Tudorascu, D. L., Cohen, A., Cody, K. A., Ances, B., Laymon, C. M., Klunk, W. E., Zaman, S., Handen, B. L., Hartley, S. L., Alexander, A. L., & Christian, B. T. (2022). White matter microstructure associations to amyloid burden in adults with Down syndrome. NeuroImage. Clinical, 33, 102908. https://doi.org/10.1016/j.nicl.2021.102908

Vogt, N. M., Hunt, J., Adluru, N., Ma, Y., Van Hulle, C. A., Doug III, D., Kecskemeti, S. R., Chin, N. A., Carlsson, C. M., Asthana, S., Johnson, S. C., Kollmorgen, G., Batrla, R., Wild, N., Buck, K., Zetterberg, H., Alexander, A. L., Blennow, K., & Bendlin, B. B. (2022). Interaction of amyloid and tau on cortical microstructure in cognitively unimpaired adults. Alzheimer’s & dementia: the journal of the Alzheimer’s Association, 18(1):65-76. doi: 10.1002/alz.12364.

Ennis, G. E., Kohli, A., Jonaitis, E. M., Betthauser, T. J., Oh, J. M., Taylor, C. E., Chin, N., Koscik, R. L., Christian, B. T., Asthana, S., Johnson, S. C., & Bendlin, B. B. (2021). The relationship of glucose-stimulated insulin secretion to cerebral glucose metabolism and cognition in healthy middle-aged and older adults. Neurobiology of aging, 105, 174–185. https://doi.org/10.1016/j.neurobiolaging.2021.04.028

Bruno, D., Mueller, K. D., Betthauser, T., Chin, N., Engelman, C. D., Christian, B., Koscik, R. L., & Johnson, S. C. (2021). Serial position effects in the Logical Memory Test: Loss of primacy predicts amyloid positivity. Journal of neuropsychology, 15(3), 448–461. https://doi.org/10.1111/jnp.12235

Vogt, N. M., Hunt, J., Ma, Y., Van Hulle, C. A., Adluru, N., Chappell, R. J., Lazar, K. K., Jacobson, L. E., Austin, B. P., Asthana, S., Johnson, S. C., Bendlin, B. B., & Carlsson, C. M. (2021). Effects of simvastatin on white matter integrity in healthy middle-aged adults. Annals of clinical and translational neurology, 8(8), 1656–1667. https://doi.org/10.1002/acn3.51421

Ennis, G. E., Koscik, R. L., Ma, Y., Jonaitis, E. M., Van Hulle, C. A., Betthauser, T. J., Randall, A. M., Chin, N., Engelman, C. D., Anderson, R., Suridjan, I., Kollmorgen, G., Christian, B. T., Carlsson, C. M., Asthana, S., Johnson, S. C., Zetterberg, H., Blennow, K., & Bendlin, B. B. (2021). Insulin resistance is related to cognitive decline but not change in CSF biomarkers of Alzheimer’s disease in non-demented adults. Alzheimer’s & dementia (Amsterdam, Netherlands), 13(1), e12220. https://doi.org/10.1002/dad2.12220

Mueller, K. D., Van Hulle, C. A., Koscik, R. L., Jonaitis, E., Peters, C. C., Betthauser, T. J., Christian, B., Chin, N., Hermann, B. P., & Johnson, S. (2021). Amyloid beta associations with connected speech in cognitively unimpaired adults. Alzheimer’s & dementia (Amsterdam, Netherlands), 13(1), e12203. https://doi.org/10.1002/dad2.12203

Bazydlo, A., Zammit, M., Wu, M., Dean, D., Johnson, S., Tudorascu, D., Cohen, A., Cody, K., Ances, B., Laymon, C., Klunk, W., Zaman, S., Handen, B., Alexander, A., Christian, B., & Hartley, S. (2021). White matter microstructure associations with episodic memory in adults with Down syndrome: a tract-based spatial statistics study. Journal of neurodevelopmental disorders, 13(1), 17. https://doi.org/10.1186/s11689-021-09366-1

Mueller, K. D., Koscik, R. L., Du, L., Bruno, D., Jonaitis, E. M., Koscik, A. Z., Christian, B. T., Betthauser, T. J., Chin, N. A., Hermann, B. P., & Johnson, S. C. (2020). Proper names from story recall are associated with beta-amyloid in cognitively unimpaired adults at risk for Alzheimer’s disease. Cortex; a journal devoted to the study of the nervous system and behavior, 131, 137–150. https://doi.org/10.1016/j.cortex.2020.07.008

Cody, K. A., Piro-Gambetti, B., Zammit, M. D., Christian, B. T., Handen, B. L., Klunk, W. E., Zaman, S., Johnson, S. C., Plante, D. T., & Hartley, S. L. (2020). Association of sleep with cognition and beta amyloid accumulation in adults with Down syndrome. Neurobiology of aging, 93, 44–51. https://doi.org/10.1016/j.neurobiolaging.2020.04.018

Vogt NM, Hunt JF, Adluru N, Dean DC, Johnson SC, Asthana S, Yu JJ, Alexander AL, Bendlin BB. (2020). Cortical Microstructural Alterations in Mild Cognitive Impairment and Alzheimer’s Disease Dementia. Cerebral Cortex, 30(5):2948-2960. doi: 10.1093/cercor/bhz286.

Zammit MD, Laymon CM, Betthauser TJ, Cody KA, Tudorascu DL, Minhas DS, Sabbagh MN, Johnson SC, Zaman SH, Mathis CA, Klunk WE, Handen BL, Cohen AD, Christian BT. (2020). Amyloid accumulation in Down syndrome measured with amyloid load. Alzheimer’s & Dementia, 12(1):e12020. doi: 10.1002/dad2.12020. PMID: 32435686; PMCID: PMC7233422.

Betthauser TJ, Koscik RL, Jonaitis EM, Allison SL, Cody KA, Erickson CM, Rowley HA, Stone CK, Mueller KD, Clark LR, Carlsson CM, Chin NA, Asthana S, Christian BT, Johnson SC. (2020). Amyloid and tau imaging biomarkers explain cognitive decline from late middle-age. Brain, 143(1):320-335. doi: 10.1093/brain/awz378.

Hwang SJ, Adluru N, Kim WH, Johnson SC, Bendlin BB, Singh V. (2019). Associations Between Positron Emission Tomography Amyloid Pathology and Diffusion Tensor Imaging Brain Connectivity in Pre-Clinical Alzheimer’s Disease. Brain Connections, 9(2):162-173. doi: 10.1089/brain.2018.0590.

Clark LR, Koscik RL, Allison SL, Berman SE, Norton D, Carlsson CM, Betthauser TJ, Bendlin BB, Christian BT, Chin NA, Asthana S, Johnson SC. (2019). Hypertension and obesity moderate the relationship between β-amyloid and cognitive decline in midlife. Alzheimers & Dementia, 15(3):418-428. doi: 10.1016/j.jalz.2018.09.008.

Tudorascu DL, Anderson SJ, Minhas DS, Yu Z, Comer D, Lao P, Hartley S, Laymon CM, Snitz BE, Lopresti BJ, Johnson S, Price JC, Mathis CA, Aizenstein HJ, Klunk WE, Handen BL, Christian BT, Cohen AD. (2019). Comparison of longitudinal Aβ in nondemented elderly and Down syndrome. Neurobiology of Aging, 73:171-176. doi: 10.1016/j.neurobiolaging.2018.09.030.

Betthauser TJ, Cody KA, Zammit MD, Murali D, Converse AK, Barnhart TE, Stone CK, Rowley HA, Johnson SC, Christian BT. (2019). In vivo characterization and quantification of neurofibrillary tau PET radioligand [¹⁸F]MK-6240 in humans from Alzheimer’s disease dementia to young controls. Journal of Nuclear Medicine, 60(1):93-99. doi: 10.2967/jnumed.118.209650.

Pozorski V, Oh JM, Adluru N, Merluzzi AP, Theisen F, Okonkwo O, Barzgari A, Krislov S, Sojkova J, Bendlin BB, Johnson SC, Alexander AL, Gallagher CL. (2018). Longitudinal white matter microstructural change in Parkinson’s disease. Human Brain Mapping, 39(10):4150-4161. doi: 10.1002/hbm.24239.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Hartley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Johnson SC, Klunk WE, Christian BT. (2018). Alzheimer-Like Pattern of Hypometabolism Emerges with Elevated Amyloid-β Burden in Down Syndrome. Journal of Alzheimers Disease, 61(2):631-644. doi: 10.3233/JAD-170720.

Betthauser TJ, Ellison PA, Murali D, Lao PJ, Barnhart TE, Furumoto S, Okamura N, Johnson SC, Engle JW, Nickles RJ, Christian BT. (2017) Characterization of the radiosynthesis and purification of [18F]THK-5351, a PET ligand for neurofibrillary tau. Applied Radiation and Isotopes. 130:230-237.

Darst BF, Koscik RL, Racine AM, Oh JM, Krause RA, Carlsson CM, Zetterberg H, Blennow K, Christian BT, Bendlin BB, Okonkwo OC, Hogan KJ, Hermann BP, Sager MA, Asthana S, Johnson SC, Engelman CD. (2017) Pathway-Specific Polygenic Risk Scores as Predictors of Amyloid-β Deposition and Cognitive Function in a Sample at Increased Risk for Alzheimer’s Disease. Journal of Alzheimer’s Disease, 55(2):473-484.

Dougherty RJ, Schultz SA, Kirby TK, Boots EA, Oh JM, Edwards D, Gallagher CL, Carlsson CM, Bendlin BB, Asthana S, Sager MA, Hermann BP, Christian BT, Johnson SC, Cook DB, Okonkwo OC. (2017) Moderate Physical Activity is Associated with Cerebral Glucose Metabolism in Adults at Risk for Alzheimer’s Disease. Journal of Alzheimer’s Disease. 58(4):1089-1097.

Hartley SL, Handen BL, Devenny D, Mihaila I, Hardison R, Lao PJ, Klunk WE, Bulova P, Johnson SC, Christian BT. (2017) Cognitive decline and brain amyloid-β accumulation across 3 years in adults with Down syndrome. Neurobiology of Aging. 58:68-76.

Mihaila I, Hartley SL, Handen BL, Bulova PD, Tumuluru RV, Devenny DA, Johnson SC, Lao PJ, Christian BT. (2017) Leisure Activity and Caregiver Involvement in Middle-Aged and Older Adults With Down Syndrome. Intellectual and Developmental Disabilities. 55(2):97-109.

Theisen F, Leda R, Pozorski V, Oh JM, Adluru N, Wong R, Okonkwo O, Dean DC 3rd, Bendlin BB, Johnson SC, Alexander AL, Gallagher CL. (2017). Evaluation of striatonigral connectivity using probabilistic tractography in Parkinson’s disease. Neuroimage Clinical, 9;16:557-563. doi: 10.1016/j.nicl.2017.09.009

Nicholas CR, Hoscheidt SM, Clark LR, Racine AM, Berman SE, Koscik RL, Maritza Dowling N, Asthana S, Christian BT, Sager MA, Johnson SC. (2017) Positive affect predicts cerebral glucose metabolism in late middle-aged adults. Social Cognitive and Affective Neuroscience. 12(6):993-100. 12(6):993-100.

Betthauser TJ, Lao PJ, Murali D, Barnhart TE, Furumoto S, Okamura N, Stone CK, Johnson SC, Christian BT. (2017) In vivo comparison of tau radioligands [18F]THK-5351 and [18F]THK-5117. Journal of Nuclear Medicine. 58(6):996-1002.

Boots EA, Schultz SA, Clark LR, Racine AM, Darst BF, Koscik RL, Carlsson CM, Gallagher CL, Hogan KJ, Bendlin BB, Asthana S, Sager MA, Hermann BP, Christian BT, Dubal DB, Engelman CD, Johnson SC, Okonkwo OC. (2017) BDNF Val66Met predicts cognitive decline in the Wisconsin Registry for Alzheimer’s Prevention. Neurology. 88(22):2098-2106.

Lao PJ, Handen BL, Betthauser TJ, Mihaila I, Harley SL, Cohen AD, Tudorascu DL, Bulova PD, Lopresti BJ, Tumuluru RV, Murali D, Mathis CA, Barnhart TE, Stone CK, Price JC, Devenny DA, Mailick MR, Klunk WE, Johnson SC, Christian BT. (2017) Longitudinal changes in amyloid positron emission tomography and volumetric magnetic resonance imaging in the nondemented Down syndrome population. Alzheimer’s & Dementia. 23(9):1-9.

Dean DC 3rd, Hurley SA, Kecskemeti SR, O’Grady JP, Canda C, Davenport-Sis NJ, Carlsson CM, Zetterberg H, Blennow K, Asthana S, Sager MA, Johnson SC, Alexander AL, Bendlin BB. (2017) Association of Amyloid Pathology With Myelin Alteration in Preclinical Alzheimer Disease. JAMA Neurology, 74(1):41-49. doi: 10.1001/jamaneurol.2016.3232.

Racine AM, Koscik RL, Nicholas CR, Clark LR, Okonkwo OC, Oh JM, Hillmer AT, Murali D, Barnhart TE, Betthauser TJ, Gallagher CL, Rowley HA, Dowling NM, Asthana S, Bendlin BB, Blennow K, Zetterberg H, Carlsson CM, Christian BT, Johnson SC. (2016) Cerebrospinal fluid ratios with Aβ42 predict preclinical brain β-amyloid accumulation. Alzheimer’s & Dementia. 2:27-38.

Racine AM, Clark LR, Berman SE, Koscik RL, Mueller KD, Norton D, Nicholas CR, Blennow K, Zetterberg H, Jedynak B, Bilgel M, Carlsson CM, Christian BT, Asthana S, Johnson SC. (2016) Associations between Performance on an Abbreviated CogState Battery, Other Measures of Cognitive Function, and Biomarkers in People at Risk for Alzheimer’s Disease. Journal of Alzheimer’s Disease. 18;54(4):1395-1408.

Dean DC 3rd, Sojkova J, Hurley S, Kecskemeti S, Okonkwo O, Bendlin BB, Theisen F, Johnson SC, Alexander AL, Gallagher CL. (2016) Alterations of Myelin Content in Parkinson’s Disease: A Cross-Sectional Neuroimaging Study. PLoS One. 5;11(10):e0163774. doi: 10.1371/journal.pone.0163774.

Merluzzi AP, Dean DC 3rd, Adluru N, Suryawanshi GS, Okonkwo OC, Oh JM, Hermann BP, Sager MA, Asthana S, Zhang H, Johnson SC, Alexander AL, Bendlin BB. (2016) Age-dependent differences in brain tissue microstructure assessed with neurite orientation dispersion and density imaging. Neurobiology of Aging. 43:79-88. doi: 10.1016/j.neurobiolaging.2016.03.026.

Lao PJ, Betthauser TJ, Hillmer AT, Price JC, Klunk WE, Mihaila I, Higgins AT, Bulova PD, Hartley SL, Hardison R, Tumuluru RV, Murali D, Mathis CA, Cohen AD, Barnhart TE, Devenny DA, Mailick MR, Johnson SC, Handen BL, Christian BT. (2016) The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by carbon 11-labeled Pittsburgh compound B. Alzheimer’s & Dementia. 12(4):380-390.

Gallagher CL, Bell B, Palotti M, Oh J, Christian BT, Okonkwo O, Sojkova J, Buyan-Dent L, Nickles RJ, Harding SJ, Stone CK, Johnson SC, Holden JE. (2015) Anterior cingulate dopamine turnover and behavior change in Parkinson’s disease. Brain Imagining and Behavior. 9(4):821-827.

Schultz SA, Larson J, Oh J, Koscik R, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, Asthana S, Hermann BP, Johnson SC, Sager M, LaRue A, Okonkwo OC. (2015) Participation in cognitively-stimulating activities is associated with brain structure and cognitive function in preclinical Alzheimer’s disease. Brain Imaging and Behavior, 9(4):729-36. doi: 10.1007/s11682-014-9329-5.

Schultz SA, Boots EA, Almeida RP, Oh JM, Einerson J, Korcarz CE, Edwards DF, Koscik RL, Dowling MN, Gallagher CL, Bendlin BB, Christian BT, Zetterberg H, Blennow K, Carlsson CM, Asthana S, Hermann BP, Sager MA, Johnson SC, Stein JH, Okonkwo OC. (2015) Cardiorespiratory Fitness Attenuates the Influence of Amyloid on Cognition. Journal of the International Neuropsychological Society: JINS, 21(10), 841–850. https://doi.org/10.1017/S1355617715000843

Darst BF, Koscik RL, Hermann BP, La Rue A, Sager MA, Johnson SC, Engelman CD. (2015) Heritability of cognitive traits among siblings with a parental history of Alzheimer’s disease. Journal of Alzheimer’s Disease. 1;45(4):1149-55. doi: 10.3233/JAD-142658.

Berman SE, Rivera-Rivera LA, Clark LR, Racine AM, Keevil JG, Bratzke LC, Carlsson CM, Bendlin BB, Rowley HA, Blennow K, Zetterberg H, Asthana S, Turski P, Johnson SC, Wieben O. (2015) Intracranial Arterial 4D-Flow is Associated with Metrics of Brain Health and Alzheimer’s Disease. Alzheimers and Dementia (Amst). 1;1(4):420-428..

Schultz SA, Oh JM, Koscik RL, Dowling NM, Gallagher CL, Carlsson CM, Bendlin BB, LaRue A, Hermann BP, Rowley HA, Asthana S, Sager MA, Johnson SC, Okonkwo OC. (2015) Subjective memory complaints, cortical thinning, and cognitive dysfunction in middle-aged adults at risk for AD. Alzheimer’s & Dementia. 1;1(1):33-40.

Kim WH, Adluru N, Chung MK, Okonkwo OC, Johnson SC, B Bendlin B, Singh V. (2015) Multi-resolution statistical analysis of brain connectivity graphs in preclinical Alzheimer’s disease. Neuroimage. 27;118:103-117. doi: 10.1016/j.neuroimage.2015.05.050.

Willette AA, Johnson SC, Birdsill AC, Sager MA, Christian B, Baker LD, Craft S, Oh J, Statz E, Hermann BP, Jonaitis EM, Koscik RL, La Rue A, Asthana S, Bendlin BB. (2015) Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimer’s & Dementia. 11(5):504-510.e1. doi: 10.1016/j.jalz.2014.03.011.

Sprecher KE, Bendlin BB, Racine AM, Okonkwo OC, Christian BT, Koscik RL, Sager MA, Asthana S, Johnson SC, Benca RM. (2015) Amyloid burden is associated with self-reported sleep in nondemented late middle-aged adults. Neurobiol Aging. 36(9):2568-76. doi: 10.1016/j.neurobiolaging.2015.05.004.

Willette AA, Bendlin BB, Starks EJ, Birdsill AC, Johnson SC, Christian BT, Okonkwo OC, La Rue A, Hermann BP, Koscik RL, Jonaitis EM, Sager MA, Asthana S. (2015) Association of Insulin Resistance With Cerebral Glucose Uptake in Late Middle-Aged Adults at Risk for Alzheimer Disease.. JAMA Neurology. 72(9):1013-20. doi: 10.1001/jamaneurol.2015.0613.

Boots EA, Schultz SA, Oh JM, Larson J, Edwards D, Cook D, Koscik RL, Dowling MN, Gallagher CL, Carlsson CM, Rowley HA, Bendlin BB, LaRue A, Asthana S, Hermann BP, Sager MA, Johnson SC, Okonkwo OC. (2015) Cardiorespiratory fitness is associated with brain structure, cognition, and mood in a middle-aged cohort at risk for Alzheimer’s disease. Brain Imaging and Behavior, 9(3):639-49. doi: 10.1007/s11682-014-9325-9.

Almeida RP, Schultz SA, Austin BP, Boots EA, Dowling NM, Gleason CE, Bendlin BB, Sager MA, Hermann BP, Zetterberg H, Carlsson CM, Johnson SC, Asthana S, Okonkwo OC. (2015) Effect of Cognitive Reserve on Age-Related Changes in Cerebrospinal Fluid Biomarkers of Alzheimer Disease. JAMA Neurology, 72(6):699-706. doi: 10.1001/jamaneurol.2015.0098.

Mielke MM, Haughey NJ, Bandaru VV, Zetterberg H, Blennow K, Andreasson U, Johnson SC, Gleason CE, Blazel HM, Puglielli L, Sager MA, Asthana S, Carlsson CM. (2014) Cerebrospinal fluid sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer’s disease. Neurobiology of Aging. 35(11):2486-94. doi: 10.1016/j.neurobiolaging.2014.05.019.

Hartley SL, Handen BL, Devenny DA, Hardison R, Mihaila I, Price JC, Cohen AD, Klunk WE, Mailick MR, Johnson SC, Christian BT. (2014) Cognitive functioning in relation to brain amyloid-β in healthy adults with Down syndrome. Brain. 137(Pt 9):2556-63.

Johnson SC, Christian BT, Okonkwo OC, Oh JM, Harding S, Xu G, Hillmer AT, Wooten DW, Murali D, Barnhart TE, Hall LT, Racine AM, Klunk WE, Mathis CA, Bendlin BB, Gallagher CL, Carlsson CM, Rowley HA, Hermann BP, Dowling NM, Asthana S, Sager MA. (2014) Amyloid burden and neural function in people at risk for Alzheimer’s Disease. Neurobiology of Aging. 35(3):576-84.

Okonkwo OC, Oh JM, Koscik R, Jonaitis E, Cleary CA, Dowling NM, Bendlin BB, Larue A, Hermann BP, Barnhart TE, Murali D, Rowley HA, Carlsson CM, Gallagher CL, Asthana S, Sager MA, Christian BT, Johnson SC. (2014) Amyloid burden, neuronal function, and cognitive decline in middle-aged adults at risk for Alzheimer’s disease. Journal of the International Neuropsychological Society. 20(4):422-33.

Okonkwo OC, Schultz SA, Oh JM, Larson J, Edwards D, Cook D, Koscik R, Gallagher CL, Dowling NM, Carlsson CM, Bendlin BB, LaRue A, Rowley HA, Christian BT, Asthana S, Hermann BP, Johnson SC, Sager MA. (2014) Physical activity attenuates age-related biomarker alterations in preclinical AD. Neurology. 4;83(19):1753-60. doi: 10.1212/WNL.0000000000000964.

Willette AA, Coe CL, Birdsill AC, Bendlin BB, Colman RJ, Alexander AL, Allison DB, Weindruch RH, Johnson SC. (2013) Interleukin-8 and interleukin-10, brain volume and microstructure, and the influence of calorie restriction in old rhesus macaques. Age. Mar 6.

Willette AA, Xu G, Johnson SC, Birdsill AC, Jonaitis EM, Sager MA, Hermann BP, La Rue A, Asthana S, Bendlin BB. (2013) Insulin resistance, brain atrophy, and cognitive performance in late middle-aged adults. Diabetes Care. Feb;36(2):443-9.

Sridharan A, Pehar M, Salamat MS, Pugh TD, Bendlin BB, Willette AA, Anderson RM, Kemnitz JW, Colman RJ, Weindruch RH, Puglielli L, Johnson SC. (2013) Calorie restriction attenuates astrogliosis but not amyloid plaque load in aged rhesus macaques: a preliminary quantitative imaging study. Brain Research. May 1;1508:1-8.

Gallagher C, Bell B, Bendlin B, Palotti M, Okonkwo O, Sodhi A, Wong R, Buyan-Dent L, Johnson S, Wilette A, Harding S, Ninman N, Kastman E, Alexander A. (2013) White Matter Microstructural Integrity and Executive Function in Parkinson’s Disease. Journal of the International Neuropsychological Society. 19(3):349-54.

Ries ML, McLaren DG, Bendlin BB, Guofanxu, Rowley HA, Birn R, Kastman EK, Sager MA, Asthana S, Johnson SC. (2012) Medial prefrontal functional connectivity-Relation to memory self-appraisal accuracy in older adults with and without memory disorders. Neuropsychologia. Apr;50(5):603-11.

Okonkwo OC, Xu G, Oh JM, Dowling NM, Carlsson CM, Gallagher CL, Birdsill AC, Palotti M, Wharton W, Hermann BP, Larue A, Bendlin BB, Rowley HA, Asthana S, Sager MA, Johnson SC. (2012) Cerebral Blood Flow is Diminished in Asymptomatic Middle-Aged Adults with Maternal History of Alzheimer’s Disease. Cerebral Cortex. Dec 12.

Birdsill AC, Carlsson CM, Willette AA, Okonkwo OC, Johnson SC, Xu G, Oh JM, Gallagher CL, Koscik RL, Jonaitis EM, Hermann BP, Larue A, Rowley HA, Asthana S, Sager MA, Bendlin BB. (2012) Low cerebral blood flow is associated with lower memory function in metabolic syndrome. Obesity. Nov 30.

Carlsson CM, Xu G, Wen Z, Barnet JH, Blazel HM, Chappell RJ, Stein JH, Asthana S, Sager MA, Alsop DC, Rowley HA, Fain SB, Johnson SC. (2011) Effects of Atorvastatin on Cerebral Blood Flow in Middle-Aged Adults at Risk for Alzheimer’s Disease: A Pilot Study. Current Alzheimer Research. 2011 Nov 28. [Epub ahead of print].

Willette AA, Coe CL, Colman RJ, Bendlin BB, Kastman EK, Field AS, Alexander AL, Allison DB, Weindruch RH, Johnson SC. (2011) Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys. Psychoneuroendocrinology. 2011 Nov 24. [Epub ahead of print].

Johnson SC, La Rue A, Hermann BP, Xu G, Koscik RL, Jonaitis EM, Bendlin BB, Hogan KJ, Roses AD, Saunders AM, Lutz MW, Asthana S, Green RC, Sager MA. (2011) The effect of TOMM40 poly-T length on gray matter volume and cognition in middle-aged persons with APOE ε3/ε3 genotype. Alzheimers & Dementia. Jul;7(4):456-65.

Austin BP, Nair VA, Meier TB, Xu G, Rowley HA, Carlsson CM, Johnson SC, Prabhakaran V. (2011) Effects of hypoperfusion in Alzheimer’s disease. Journal of Alzheimers Disease. 26 Suppl 3:123-33.

Sterling C. Johnson, PhD

Contact Information

Research Statement

Selected Publications