Qiang Chang, PhD
Director, Waisman Center
Core Director, Rodent Models
Professor of Medical Genetics & Neurology
608-262-9416 | Room 657
Qiang Chang, PhD, is a professor of medical genetics and neurology, associate director of the Waisman Center Intellectual & Developmental Disabilities Research Center and faculty co-director of the Rodent Models Core.
Chang completed his BS in biochemistry and molecular biology at Peking University in Beijing, PR China and earned his PhD in neurosciences from the University of Pennsylvania School of Medicine. As a postdoctoral fellow, he studied neural regeneration at Children’s Hospital of Boston/Harvard Medical School, and neurological diseases at the Whitehead Institute/MIT.
Qiang’s laboratory at the Waisman Center is interested in the DNA methylation dependent epigenetic regulation of mammalian brain development and function, with a particular emphasis on understanding the molecular mechanism of Rett syndrome, an autism spectrum developmental disorder.
Christian is a professor in medical physics and psychiatry and will provide overall leadership for the application of the PET molecular imaging for research studies. He is an expert in PET neuroreceptor imaging, and has conducted studies in preclinical animal models for radiotracer development and characterization and translated these methods to human and disease specific cohorts. The PET lab is currently conducting investigations with a variety of PET neuroligands, including 2 first-in-human investigations, and is the recent recipient of an NICHD/NIA jointly funded multi-investigator grant to identify biomarkers such as β-amyoid and tau for studying dementia in adults with Down syndrome. Christian directs all aspects of PET research in the Core, including the human PET scanner and radiopharmaceutical development and the provision of training and consultation to investigators on the use of neuroligands for PET imaging of neurotransmitter and molecular function.