Tuberous Sclerosis Complex (TSC) is an autosomal dominant neurodevelopmental disorder caused by a monogenic mutation to either TSC1 or TSC2. Nearly one-half of TSC patients have mild to profound intellectual disabilities and autism, with the majority developing seizures and neuropsychiatric conditions.
Austin Pier
Austin Pier (Gomez laboratory) – Slide of the Week
Re-expression of Halo-TSC2 for 1 DIV in TSC2-/- cortical neurons reduces hyper-phosphorylated S6 and increased neurite length