The segmentation of small brain structures like the amygdala is quite challenging in the presence of distorted and abnormal anatomy from major brain injuries.
Strong genetic associations have been found for a number of psychiatric disorders. However, understanding the underlying molecular mechanisms remains challenging.
Autism is a neurodevelopmental disorder that manifests as a heterogeneous set of social, cognitive, motor, and perceptual symptoms. This system-wide pervasiveness suggests that, rather than narrowly impacting individual systems such as affection or vision, autism may broadly alter neural computation.
The size and shape of human cervical vertebral bodies serve as a reference for measurement or treatment planning in multiple disciplines. It is therefore necessary to understand thoroughly the developmental changes in the cervical vertebrae in relation to the changing biomechanical demands on the neck during the first two decades of life.
Individuals with autism spectrum disorder often struggle with motor difficulties across the life span, and these motor difficulties may affect independent living skills and quality of life. Yet, we know little about how whole-body movement may distinguish individuals with autism spectrum disorder from individuals with typical development.
Loss of vision can frequently lead to a loss of independence and a reduction in quality of life for an individual. The Tekin lab is interested in harnessing new mobile technologies to provide access to environmental information for persons with vision loss.
Peripheral nerve myelination is adversely affected in the most common form of the hereditary peripheral neuropathy called Charcot-Marie-Tooth Disease. This form, classified as CMT1A, is caused by a 1.4 Mb duplication on chromosome 17, which includes the abundantly expressed Schwann cell myelin gene, Peripheral Myelin Protein 22 (PMP22).
Human induced pluripotent stem cells (iPSCs) present exciting opportunities to study disease processes in vitro. Advances in bioengineering allow us to differentiate cells in a system more relevant to their native environment in order to observe naturally occurring phenomena.
This study investigated the production of demonstratives (e.g., this, that, these) and personal pronouns in school-age boys with idiopathic autism spectrum disorder (ASD) and school-age boys with fragile X syndrome (FXS) with a co-diagnosis of ASD (FXS+ASD).
Can brief messages about health influence children’s consumption of identical foods? Across a series of studies, we manipulated children’s consumption of identical foods (fruit sauces) by pairing those foods with brief messages about each food’s health status.