Austin Pier & Ngawang Namru (Gomez Laboratory) – Slide of the Week

Tuberous Sclerosis Complex (TSC) is an autosomal dominant neurodevelopmental disorder caused by a monogenic mutation to either TSC1 or TSC2. Nearly one-half of TSC patients have mild to profound intellectual disabilities and autism, with the majority developing seizures and neuropsychiatric conditions.

Christopher L. Coe, PhD – Slide of the Week

Female monkeys were vaccinated with spike protein from the ancestral virus (Wuhan) or an early variant (Gamma). Their infants had high levels of maternal IgG at birth, which more specifically inhibited the virus against which their mother had been immunized.

Max McLachlan (Christian Lab) Slide of the Week

Adults with Down syndrome demonstrate striatum-first amyloid accumulation with [11C]Pittsburgh Compound-B (PiB) positron emission tomography (PET) imaging, which has not been replicated with [18F]florbetapir (FBP). Early striatal accumulation has not been temporally quantified with respect to global cortical measures.