Seminar – Yong-hui Jiang, MD, PhD – “Modeling Autism by SHANK3 and H1-4 Gene Mutations: Synaptic Dysfunction vs Epigenetic Dysregulation”

I am physician scientist active both in basic research and clinical practice. My research interests are to 1) uncover the genetic and epigenetic bases of neurodevelopmental disorders or rare diseases with neurodevelopmental defects; 2) model genetic diseases using human patients derived cellular models and genetic mutant mice; 3) understand the circuit and molecular mechanisms underlying autism spectrum disorder; 4) develop novel molecular and epigenetic targeted therapies for genetic and epigenetic diseases.