Christopher L. Coe, PhD – Slide of the Week

Female monkeys were vaccinated with spike protein from the ancestral virus (Wuhan) or an early variant (Gamma). Their infants had high levels of maternal IgG at birth, which more specifically inhibited the virus against which their mother had been immunized.

Christopher Coe, PhD – Slide of the Week

The developing immune system is an adaptive system, primed by antigens, responsive to infectious pathogens, and can be affected by other aspects of the early rearing environment, including deviations from the normal provision of parental care. We investigated whether early rearing in an institutional setting, even when followed by years living in supportive and well-resourced families, would be associated with a persistent shift in T cell profiles.