Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
A blood test alone cannot tell the full story of what’s happening inside a newborn’s brain after a brain injury. New research from the Waisman Center at the University of Wisconsin-Madison suggests that the hippocampus—a brain region critical for learning and memory—maintains its own powerful, locally regulated steroid environment during early development and after brain injury.
The purpose of the present study was to investigate the hypothesis that women with autism have poorer health compared with men with autism, and compared with women without autism.
Autism spectrum disorder (ASD) is consistently diagnosed 3 to 5 times more frequently in males than females, a dramatically sex-biased prevalence that suggests the involvement of sex-differential biological factors in modulating risk. The genomic scale of transcriptomic analyses of human brain tissue can provide an unbiased approach for identifying genes and associated functional processes at the intersection of sex-differential and ASD-impacted neurobiology.
