Category: Intellectual and Developmental Disabilities (IDD)

A dynamic map of early brain development captures major drivers of neurogenesis

At a Glance: A map of early brain development that captures its major drivers and their dynamics through time has been developed by Waisman Center investigators. Compiling different brain regions across three different species including humans, the new blueprint can identify the upstream regulators of brain development, evolution, and disorder risk, revealing how highly complex …

New screening platform accelerates search for Rett syndrome treatments and reveals new disease mechanisms

At a Glance: Developing treatments for rare genetic disorders, such as Rett syndrome, is notoriously difficult, often requiring years of research and significant financial investment. Researchers at the Waisman Center, University of Wisconsin–Madison have developed a new drug screening platform for Rett syndrome that could help accelerate the search for potential therapies while uncovering new …

RNA-binding protein identified as key regulator of brain development

A new Waisman Center, University of Wisconsin-Madison study has identified a critical regulator of this early process of cell fate called FXR1, a protein that binds RNA to regulate the abundance of key genes.

New drug shows promise for treating Down syndrome-related brain changes

Individuals with Down syndrome have differences in how their brains form that cause intellectual disability. Down syndrome or trisomy 21 is the most common genetic cause of intellectual and developmental disability and is caused by the triplication of chromosome 21.

Lawrence University senior takes on language development research at Waisman

Giang Pham, a rising senior from Lawrence University in Appleton, is spending her second summer doing research at the Waisman Center University of Wisconsin–Madison as part of an internship program established and supported by the late John Mielke, MD, a former member of the Waisman Board of Visitors and Appleton native, and his wife Sally. …

Puerto Rico to become a site for The Alzheimer Biomarker Consortium – Down syndrome

Puerto Rican families have started traveling to Wisconsin to be part of the research study, but the goal is to build the infrastructure to eventually conduct the studies on the island.

A springboard for scientific independence: Inside Waisman’s T32 Postdoctoral Training Program

At a Glance: Postdoctoral fellowships occupy an unusual space between being a graduate student and becoming an independent scholar. The postdoc stage is marked by a focus on refining research skills, expanding their knowledge-base, and developing key professional development skills (e.g., grant writing) needed to be an independent scientist. It can feel at times, like …

Family-Led Academic Grand (FLAG) Rounds: Family stories as a tool for teaching patient and family-centered care to medical trainees

FLAG Rounds were developed by Coleman and Danielle Gerber to use family faculty, or family members of children with complex medical needs as lecturers, and storytelling as a strategy to develop the knowledge, skills, and attitude in medical students and providers to dismantle ableism in pediatric care and partner with families in the care of their children.

Typing, tapping, and eye-gaze tracking: Augmentative and alternative communication provides crucial access to communication when speech is out of reach

For many, talking is as easy as breathing. A few words to tell your friend that you are hungry and ready for lunch. A long rant to your partner about frustrations at work. A description of what hurts to your doctor. A quiet, ‘I love you,’ to a close family member. Being able to talk helps to make communicating efficient and effective. But not everyone has access to speech.

New book shares the experiences of individuals with disabilities through the COVID-19 pandemic using photos

The Pandemic Cancelled It, and They Never Brought It Back takes readers into the daily lives of individuals with intellectual and developmental disabilities during the COVID‑19 pandemic, using their own photographs and words to reveal moments of loss, adaptation, resilience, and connection. Created by researchers at the Waisman Center, the book offers an intimate portrait of a community whose experiences are too often overlooked.