University of Wisconsin–Madison

Tag: astrocyte

New research reveals parallels between Alexander disease and other neurodegenerative conditions like Alzheimer’s disease

New research from Waisman investigator, Tracy Hagemann, PhD, associate research professor, delves into the cognitive impairments and associated molecular changes caused by Alexander disease (AxD), revealing similarities to other neurodegenerative diseases like Alzheimer’s.

Tracy L. Hagemann, PhD – Slide of the Week

Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system.