University of Wisconsin–Madison

Tag: Rosenthal fibers

Tracy L. Hagemann, PhD – Slide of the Week

Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system.

Alexander disease: A lifetime’s work in the hope of saving lives

Messing wanted to study if the overexpression of GFAP resulted in a certain reactive response in the brain.