Tracy L. Hagemann, PhD – Slide of the Week
Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system.
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Alexander disease (AxD) is caused by mutations in the gene for glial fibrillary acidic protein (GFAP), an intermediate filament expressed by astrocytes in the central nervous system.
Messing wanted to study if the overexpression of GFAP resulted in a certain reactive response in the brain.