A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.
Neurodegenerative
Waisman’s Own Takes Interim Position in OVCRGE
CMT is a slowly progressive disease in contrast to ALS, which affects the same neurons in the peripheral nervous system.
Neurodegeneration research at the Waisman Center from gene to organelle to cell to brain
Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.
In the lab where sign language advances science: A spotlight on Phu Duong
Epigenetics – the study of how environment can change and affect how genes function – was a new field for Phu Duong, PhD.
Alexander disease: A lifetime’s work in the hope of saving lives
Messing wanted to study if the overexpression of GFAP resulted in a certain reactive response in the brain.
A college degree may protect against neurodegeneration in genetically at-risk populations
Obtaining a college degree may be protective against neurodegenerative symptoms in women with an elevated genetic risk.
Weight loss may be early predictor of Alzheimer’s disease in Down syndrome
Unintentional weight loss in people with Down syndrome may predict the onset of Alzheimer’s disease long before typical cognitive symptoms like memory loss and dementia are apparent.
Lab-grown retinal eye cells make successful connections, open door for clinical trials to treat blindness
Retinal cells grown from stem cells can reach out and connect with neighbors, according to a new study, completing a “handshake” that may show the cells are ready for trials in humans with degenerative eye disorders.
Cells with a superhero alter ego: Schwann cells transform into repair cells after nerve injury with help of transcription factor JUN and Sonic Hedgehog gene
When nerves are injured, Schwann cells—a key cell in peripheral nerve function and nerve insulation—assume a new role and identity as repair cells.
Pioneering research brings potential Parkinson’s disease treatment one step closer
Over two decades of fundamental research in Parkinson’s disease led by Su-Chun Zhang, MD, PhD, professor of neuroscience and neurology at the University of Wisconsin-Madison and Waisman investigator, has culminated in the development of a promising stem cell-based treatment for the disease.