University of Wisconsin–Madison

Category: Neurodegenerative

Puerto Rico to become a site for The Alzheimer Biomarker Consortium – Down syndrome

Puerto Rican families have started traveling to Wisconsin to be part of the research study, but the goal is to build the infrastructure to eventually conduct the studies on the island.

Damage to the cerebellum impairs ability to adapt speech timing and pitch, two new studies show

Cerebellar damage may impair someone’s ability to adapt both the timing of speech and vocal pitch, new Waisman Center studies suggest, shedding light on the involvement of the cerebellum in speech motor control.

New research reveals parallels between Alexander disease and other neurodegenerative conditions like Alzheimer’s disease

New research from Waisman investigator, Tracy Hagemann, PhD, associate research professor, delves into the cognitive impairments and associated molecular changes caused by Alexander disease (AxD), revealing similarities to other neurodegenerative diseases like Alzheimer’s.

New AI framework reveals cooperative work behind oligodendrocyte function

Our brain is big on team work makes the dream work. Not only brain cells, but even smaller units that make up a cell work in cooperation to make the brain work properly.

UW-Madison’s Cool Science Image Contest: Waisman winners

Matt Zammit, PhD, Waisman scientist in the Brain Imaging Core, and affiliate investigator Erik Dent, PhD, are both winners of UW-Madison’s Cool Science Image Contest.

Taking out the trash: New study finds clearing specific cell “trash” is possible and may be target for future treatments of neurodegenerative diseases

Cells make a lot of trash. Probably more than you’d think. So, cells have a trash disposal system that efficiently cleans up and recycles any waste that is produced. But when there are issues with the disposal system and trash builds up in the cell, that can lead to disease. This has led researchers to consider the trash disposal system as a target for potential disease treatments and therapies.

Renowned Waisman investigator Su-Chun Zhang retires

After more than two decades at the Waisman Center, University of Wisconsin and several first-in-the-world stem cell scientific breakthroughs, Su-Chun Zhang, MD, PhD, professor of neuroscience and neurology, is retiring. He came to the Waisman Center in 2001 as part of the Translational Research-Neurodegenerative Diseases Cluster. Zhang anchored Waisman’s stem cell research program and has …

UW-Madison researchers first to 3D-print functional human brain tissue

A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.

Waisman’s own takes interim position in OVCRGE

CMT is a slowly progressive disease in contrast to ALS, which affects the same neurons in the peripheral nervous system.

Neurodegeneration research at the Waisman Center from gene to organelle to cell to brain

Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.