Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Low bone mineral density (BMD) and subsequent skeletal fragility have emerged as a long-term complication of phenylketonuria (PKU). The object of this study is to determine if there are differences in BMD and body composition between male and female participants with PKU.
Individuals with phenylketonuria (PKU) have a risk of cognitive impairment and inflammation. Many follow a low-phenylalanine (low-Phe) diet devoid of animal protein in combination with medical foods (MFs).
Certain kinds of foods prescribed to manage the rare metabolic disorder phenylketonuria (PKU) could contribute to skeletal fragility seen in many PKU patients, according to a new study by University of Wisconsin-Madison researchers. Led by Waisman Center and College of Agricultural and Life Sciences investigator Denise Ney and graduate student Bridget Stroup, the study represents …
Skeletal fragility is a complication of phenylketonuria (PKU). A diet containing amino acids compared to one with glycomacropeptide reduces bone size and strength in mice.
Research led by Waisman Center investigator Denise Ney has shown that food products made from a specific protein found in whey can safely be part of a more palatable diet for individuals diagnosed with phenylketonuria (PKU). Ney, who is also the Billings-Bascom Professor of Nutritional Sciences at the University of Wisconsin-Madison, focuses on individuals with …
Food products made from a specific protein found in whey can safely be part of a more palatable diet for individuals diagnosed with phenylketonuria (PKU), according to a new clinical trial led by researchers at the University of Wisconsin—Madison and Boston Children’s Hospital. “Our findings could also lead to increased insurance coverage for ‘medical foods’ …
Title: Glycomacropeptide (GMP) is a bioactive peptide released from casein in milk during cheesemaking that contains no aromatic amino acids. GMP is isolated for use in medical foods for the management of phenylketonuria (PKU) based on research conducted in Dr. Denise Ney’s laboratory at UW-Madison. GMP is an acidic, highly polar peptide that is hydrophilic …
In a rare look back in time, we’re given a glimpse into the early research and community outreach of Harry A. Waisman, MD, PhD, one of the lead researchers of Phenylketonuria (PKU), an inherited condition caused by an accumulation of the amino acid phenylalanine.
Denise Ney, professor of nutritional sciences, is a rare disease hero. We all know that, but now it’s official. Ney is one of 30 Rare Disease Heroes named by the Office of Orphan Products Development at FDA. This is part of the agency’s sixth international Rare Disease Day. This is an opportunity to reflect on what has been accomplished for rare diseases, while looking forward to the work that has yet to be done.
Mealtimes aren't quite as enjoyable for people with phenylketonuria (PKU) as they are for the rest of us.
