Low bone mineral density (BMD) and subsequent skeletal fragility have emerged as a long-term complication of phenylketonuria (PKU). The object of this study is to determine if there are differences in BMD and body composition between male and female participants with PKU.
Denise Ney, PhD – Slide of the Week
Individuals with phenylketonuria (PKU) have a risk of cognitive impairment and inflammation. Many follow a low-phenylalanine (low-Phe) diet devoid of animal protein in combination with medical foods (MFs).
New clues to healthy bones for those with PKU
Certain kinds of foods prescribed to manage the rare metabolic disorder phenylketonuria (PKU) could contribute to skeletal fragility seen in many PKU patients, according to a new study by University of Wisconsin-Madison researchers. Led by …
Denise Ney, PhD
Skeletal fragility is a complication of phenylketonuria (PKU). A diet containing amino acids compared to one with glycomacropeptide reduces bone size and strength in mice.
Foods made with special whey protein help PKU patients
Research led by Waisman Center investigator Denise Ney has shown that food products made from a specific protein found in whey can safely be part of a more palatable diet for individuals diagnosed with phenylketonuria …
A new whey to manage PKU
Food products made from a specific protein found in whey can safely be part of a more palatable diet for individuals diagnosed with phenylketonuria (PKU), according to a new clinical trial led by researchers at …
Denise Ney, PhD
Title: Glycomacropeptide (GMP) is a bioactive peptide released from casein in milk during cheesemaking that contains no aromatic amino acids. GMP is isolated for use in medical foods for the management of phenylketonuria (PKU) based …
Historic video: Harry Waisman advocates for PKU screening
In a rare look back in time, we’re given a glimpse into the early research and community outreach of Harry A. Waisman, MD, PhD, one of the lead researchers of Phenylketonuria (PKU), an inherited condition caused by an accumulation of the amino acid phenylalanine.
Denise Ney is a Rare Disease Hero
Denise Ney, professor of nutritional sciences, is a rare disease hero. We all know that, but now it’s official. Ney is one of 30 Rare Disease Heroes named by the Office of Orphan Products Development at FDA. This is part of the agency’s sixth international Rare Disease Day. This is an opportunity to reflect on what has been accomplished for rare diseases, while looking forward to the work that has yet to be done.
Medical foods for PKU diet enter phase II clinical trials
Mealtimes aren’t quite as enjoyable for people with phenylketonuria (PKU) as they are for the rest of us.