Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Applying a dramatically improved method for "editing" genes to human stem cells, University of Wisconsin-Madison neuroscientist and Waisman Center investigator Su-Chun Zhang has shown a new way to silence genes in stem cells and their progeny at any stage of development.
Fragile X syndrome is the most common inherited intellectual disability and the greatest single genetic contributor to autism. Unlocking the mechanisms behind fragile X could make important revelations about the brain.
May is ALS awareness month and Waisman Center investigator Su-Chun Zhang, MD, PhD, uses stem cells from ALS patients to uncover the cause of ALS and screen drugs to treat the disease. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord that control muscle movement. …
This story starts in 1955, upon the death of Albert Einstein, when the pathologist charged with performing the famous scientist’s autopsy stole his brain. Fast forward to the 1980s when a University of California, Berkeley scientist was studying parts of the stolen goods involved in complex thinking and discovered that the father of relativity had more of certain types of cells, called astrocytes, than other human brains studied.
When Madison attorney David Walsh learned 17 years ago that his sons have a genetic disorder that causes blindness, he went into action mode.
A recent issue of The Why Files features stem advances at the University of Wisconsin-Madison, including several scientists at the Waisman Center.
If you hadn’t heard of ALS before this summer, you’re not alone. If you haven’t heard of it by now, you must be living under a rock. Not only did the ubiquitous ALS Ice Bucket Challenge raise about $100 million from late July to late August, it boosted awareness of ALS, or amyotrophic lateral sclerosis, also known as Lou Gehrig’s disease.
By studying nerve cells that originated in patients with a severe neurological disease, a University of Wisconsin-Madison researcher has pinpointed an error in protein formation that could be the root of amyotrophic lateral sclerosis.
The 11th annual David Busta Basketball Tournament and Silent Auction once again proved successful as the benefit attracted many families, friends and community members to the Chetek-Weyerhaeuser High School Saturday, Nov. 30. After raising $26,000 at last year’s tournament and silent auction, this year’s event topped $55,000 for spinal cord injury research at the University …
From his sixth-floor laboratory in the University of Wisconsin Waisman Center, Su-Chun Zhang, MD, PhD, has a unique vantage point on the second tower of the Wisconsin Institutes for Medical Research (WIMR II), which is nearing completion.
