The electrical properties of a neuron paint a picture of its development and function. A new user-friendly and accessible tool developed at the Waisman Center allows scientists to analyze the electrical activity of individual neurons – rather than clusters – using a process known as spike sorting. The free tool is available online for other researchers to access.
Xinyu Zhao
Eagles Autism Foundation funds new research on use of nanotechnology to deliver gene-editing tools to the brain
A new research study at the Waisman Center has been funded by the Eagles Autism Foundation to develop a precise, safe, and broadly applicable method for correcting a single-gene mutation associated with symptoms of autism spectrum disorders including learning deficits, anxiety, depression, and reduced social interactions.
Waisman investigator Xinyu Zhao receives grant from the Eagles Autism Foundation
The Waisman Center celebrates the selection of Xinyu Zhao, PhD, a principal investigator renowned for her work in neural stem cells and neurodevelopment, as one of the esteemed recipients of a 2025 Eagles Autism Foundation research grant.
Undergraduate student research experience is an integral part of the Zhao lab
By Anoushka Kar The Zhao lab at the University of Wisconsin–Madison is an exciting and dedicated research entity in neuroscience which focuses on brain development and developmental disorders. It offers opportunities to students of any …
Xinyu Zhao, PhD – Slide of the Week
The human genome has many short tandem repeats, yet the normal functions of these repeats are unclear.
Genetic blueprint behind early brain development uncovered by team of Waisman investigators
Early neuronal maturation is not well understood. A new study at Waisman was able to map the gene and regulatory networks driving early neuronal maturation for the first time.
Building a better understanding of genetic repeats and their role in fragile X syndrome
Genetic repeats—a sequence or segment of DNA that is repeated over and over in a row—is a typical part of the genome. However, when there is an atypical number of repeats in the DNA sequence, it can lead to impaired gene function and be the cause of more than 50 expansion conditions including fragile X syndrome (FXS).
Waisman Center IDDRC funds three pilot projects on novel Down syndrome research
Three Waisman Center investigators and affiliates were awarded an internal grant to support Down syndrome research in its early stages. The funds were made possible through the Ann Dewey Down Syndrome Catalyst Fund at the Waisman Center.
Organoids are becoming more popular in research, consistency in their use is needed for more accurate results
To the naked eye, they look like tiny blobs free floating in a pink liquid. Under a light microscope, they look similar. But organoids, a 3-D mini version of an organ grown in a lab, may contain invaluable information about how the human brain develops.
A new grant from the Eagles Autism Foundation will help advance Waisman research on the genetic cause of autism
Studying the biological underpinnings of autism is exceptionally complex with more than 1000 genes thought to be associated with autism.