Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison reported today.
Stem Cells
Multiple gene edits and computer simulations could help treat rare genetic diseases
The lab of Kris Saha at the University of Wisconsin–Madison has developed an innovative combination of gene-editing tools and computational simulations that can be used to develop new strategies for editing genes associated with genetic disorders.
Stem cells can repair Parkinson’s-damaged circuits in mouse brains
The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson’s. Stem cells, which are endlessly adaptable, have offered the promise of better neural repair. But the brain’s precisely tuned complexity has stymied the development of clinical treatments.
UW researchers devise approach to treat rare, incurable form of blindness
Waisman Center investigator David Gamm, MD, PhD, and Waisman affiliate Kris Saha, PhD, have published a proof-of-concept method to correct Best disease – an inherited form of macular degeneration that causes blindness, and that is …
Grant awarded for eye disease research
A big congratulations to researcher Kim Edwards and Waisman investigator David Gamm, MD, PhD, on winning the inaugural Randy Wheelock Research Award. Gamm is also an associate professor of ophthalmology and visual science as well as the director of the McPherson Eye Research Institute.
Improved technique illuminates fragile X protein
Researchers at the Waisman Center made a significant step in understanding the function of a specific protein, FMR1, whose absence causes fragile X syndrome, or FXS. Waisman investigators Xinyu Zhao, PhD, and Anita Bhattacharyya, PhD, with research associate Meng Li, published their paper “Identification of FMR1-regulated molecular networks in human neurodevelopment” in the March issue of the journal Genome Research.
Newly identified cellular trash removal program helps create new neurons
New research by University of Wisconsin–Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons.
May is ALS Awareness Month
May is #ALSAwarenessMonth and Waisman investigator Su-Chun Zhang, MD, PhD, uses stem cells to uncover the cause of ALS with the hope of developing treatments and therapies.
‘This can be changed’: Verona family carries on daughter’s fight to end vision diseases
A recent story on Channel 3000 highlights the efforts by the family of Kenzi Valentyn to raise money for vision research in their daughter’s name. Waisman investigator David Gamm focuses on using stem cells to …
Lab to Clinic Video: David Gamm, MD, PhD
David Gamm, director of the McPherson Eye Research Institute, and Forward Bio Institute director Bill Murphy explain how stem cell scientists at UW–Madison are working with industry to put scientific breakthroughs on the path to …