Fragile X syndrome, the most common form of inherited intellectual disability, may be unfolding in brain cells even before birth, despite typically going undiagnosed until age 3 or later.
Fragile X syndrome (FXS) is the most common heritable form of intellectual and developmental disability. It is also the most common single genetic contributor to autism spectrum disorder (ASD).
Research studies at the Waisman Center cover both basic science and behavioral research on FXS, starting with the individual, up to the family unit, from childhood, and into old age.
Xinyu Zhao, PhD, Waisman investigator and professor of neuroscience, was recently awarded a Kellett Mid-Career Award, among 11 others, by the Office of the Vice Chancellor for Research and Graduate Education.
A recent study shows that boys with fragile X syndrome and co-occurring ASD (fragile X + ASD), and autistic boys have similar patterns of linguistic errors and omit more words in conversations compared to non-autistic boys.
Expressive language impairments are common among school-age boys with fragile X syndrome (FXS) and autistic boys.
One mutation in a single gene, as straightforward as it may sound, can cause a broad range of symptoms and severity among those who carry it. This is the case for fragile X syndrome (FXS), the most common hereditary form of intellectual disability.
Xinyu Zhao, PhD, and Anita Bhattacharyya, PhD, will partner on research over the next four years to better understand the molecular underpinnings behind the diversity of FXS symptoms and how that diversity may inform the search for effective therapies.
A newer cancer drug may also be a treatment option for a leading intellectual and developmental disability. Fragile X syndrome (FXS) is the most common form of inherited intellectual disability.
James Manlick is going to homecoming this year and he simply can’t contain his excitement. A huge smile lights up his face as he talks about the dance.