Our inability to derive the neuronal diversity that comprises the posterior central nervous system (pCNS) using human pluripotent stem cells (hPSCs) poses an impediment to understanding human neurodevelopment and disease in the hindbrain and spinal cord.
Slide of the Week
Anita Bhattacharyya, PhD – Slide of the Week
Structural pathologies, such as brain, are present at birth in Down syndrome (trisomy 21), reflecting embryonic origins that are generally associated with smaller organs or reduced growth.
Barbara B. Bendlin, PhD – Slide of the Week
White matter (WM) degeneration is a critical component of early Alzheimer’s disease (AD) pathophysiology.
Carlos Benítez-Barrera, PhD – Slide of the Week
Cultural differences in environmental auditory ecology are usually studied using geographic area monitoring.
Xinyu Zhao, PhD – Slide of the Week
Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the brain. The contribution of these targets to fragile X syndrome (FXS) and related autism spectrum disorder (ASD) remain unclear.
Karla Ausderau, PhD – Slide of the Week
Opening the door to university health research: recommendations for increasing accessibility for individuals with intellectual disability
Rebecca Alper, PhD – Slide of the Week
Using a community-based participatory research framework, we piloted Duet, a preventative, parent-implemented, early language intervention.
Andrew Alexander, PhD – Slide of the Week
Imaging-based quantitative measures from diffusion-weighted MRI (dMRI) offer the ability to non-invasively extract microscopic information from human brain tissues.
Donna Werling, PhD – Slide of the Week
Autism spectrum disorder (ASD) has a consistent 4:1 male prevalence, suggesting a role for sex-differential biology in risk.
Daifeng Wang, PhD – Slide of the Week
Our machine-learning framework, brain and organoid manifold alignment (BOMA), first performs a global alignment of developmental gene expression data between brains and organoids.