Live Stream/Online Only Learn about advances in research and clinical services and hear from a panel of experts—individuals with Down syndrome and family members. To learn more about the series visit: Waisman Center Day with …
Down syndrome
Brad Christian, PhD – Slide of the Week
PET amyloid [11C]PiB imaging has revealed early detection of Aβ in the striatum in individuals with Down Syndrome (DS), a group carrying genetic risk for AD.
Virtual Day with the Experts: Down Syndrome 2022
Live Stream/Online Only | Español Learn about advances in research and clinical services. Hosted in partnership with the Down Syndrome Association of Wisconsin-South Central (DSAW-South Central) and GiGi’s Playhouse Sponsored by the Friends of the Waisman …
Sigan Hartley, PhD – Slide of the Week
Boxplots depicting median and variation for episodic memory score by PET amyloid beta (Aβ–vs. Aβ+) and tau (TLvs. TH) status in Braakregions I to VI.
Studying the Connection Between Alzheimer’s and Down Syndrome for Down Syndrome Awareness Month
By Emily Leclerc, Waisman Science Writer The month of October is Down Syndrome Awareness Month and is dedicated to not only raising awareness about Down syndrome but also to celebrating the abilities and accomplishments of …
Stem cell project to create new model to study brain development and Down syndrome
Waisman Center researchers are creating a new approach to study how changes to brain development in the womb result in intellectual disability in people with Down syndrome.
Anita Bhattacharyya, PhD – Slide of the Week
Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology.
Houri K. Vorperian, PhD – Slide of the Week
Title: Auditory-Perceptual Features of Speech in Children and Adults with Down syndrome: A Speech Profile Analysis Legend: Table 6 – Principal component loading matrix, first four principal components, vowel features. Note. The largest loadings (in …
Sigan Hartley, PhD – Slide of the Week
There is a critical need to identify measures of cognitive functioning sensitive to early Alzheimer’s disease (AD) pathophysiology in Down syndrome to advance clinical trial research in this at-risk population. The objective of the study was to longitudinally track performance on cognitive measures in relation to neocortical and striatal amyloid beta (Aβ) in non-demented Down syndrome.
New NIH-funded initiative will examine Alzheimer’s disease in people with Down syndrome
A team of researchers at the University of Wisconsin–Madison is part of a new multi-institution effort to better understand Alzheimer’s disease in adults with Down syndrome. Adults with Down syndrome are at high risk for …