Structural pathologies, such as brain, are present at birth in Down syndrome (trisomy 21), reflecting embryonic origins that are generally associated with smaller organs or reduced growth.
Down syndrome
Waisman BioLibrary: Down Syndrome Study (Chang)
Be included! Families of children with Down syndrome are invited to participate in our new study about genetics and health. The Waisman BioLibrary is recruiting youth with Down syndrome ages 0 – 17 years. Families …
In-Person and Virtual Day with the Experts: Down Syndrome 2023
Learn about advances in research and clinical services and hear from a panel of experts—individuals with Down syndrome and family members.
Seminar – Anna Esbensen, PhD – “Improving Outcomes for Individuals with Down Syndrome”
Anna Esbensen, PhD, is an associate professor of pediatrics at the University of Cincinnati College of Medicine in the Division of Developmental and Behavioral Pediatrics at Cincinnati Children’s Hospital Medical Center. She studies the lifespan development of individuals with Down syndrome and provides clinical services to families of children with Down syndrome.
Brad Christian, PhD – Slide of the Week
PET amyloid [11C]PiB imaging has revealed early detection of Aβ in the striatum in individuals with Down Syndrome (DS), a group carrying genetic risk for AD.
Virtual Day with the Experts: Down Syndrome 2022
Live Stream/Online Only | Español Learn about advances in research and clinical services. Hosted in partnership with the Down Syndrome Association of Wisconsin-South Central (DSAW-South Central) and GiGi’s Playhouse Sponsored by the Friends of the Waisman …
Sigan Hartley, PhD – Slide of the Week
Boxplots depicting median and variation for episodic memory score by PET amyloid beta (Aβ–vs. Aβ+) and tau (TLvs. TH) status in Braakregions I to VI.
Studying the connection between Alzheimer’s and Down syndrome for Down syndrome awareness month
By Emily Leclerc, Waisman Science Writer The month of October is Down Syndrome Awareness Month and is dedicated to not only raising awareness about Down syndrome but also to celebrating the abilities and accomplishments of …
Stem cell project to create new model to study brain development and Down syndrome
Waisman Center researchers are creating a new approach to study how changes to brain development in the womb result in intellectual disability in people with Down syndrome.
Anita Bhattacharyya, PhD – Slide of the Week
Down syndrome (DS, trisomy 21) is characterized by intellectual impairment at birth and Alzheimer’s disease (AD) pathology in middle age. As individuals with DS age, their cognitive functions decline as they develop AD pathology.