Parkinson’s Disease News
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UW-Madison researchers first to 3D-print functional human brain tissue
A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.
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Neurodegeneration research at the Waisman Center from gene to organelle to cell to brain
Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis (ALS), Charcot-Marie-Tooth disease, and retinitis pigmentosa all have different manifestations and affect different body functions, but they are all connected by one mechanism: neurodegeneration.
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Scientists produce human norepinephrine neurons from stem cells, with significant implications for researching diseases like Alzheimer’s and Parkinson’s
Researchers a have identified a protein key to the development of a type of brain cell believed to play a role in disorders like Alzheimer’s and Parkinson’s diseases and used the discovery…
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Waisman investigator is only steps away from creating a potential treatment for Parkinson’s disease
When Su-Chun Zhang, MD, PhD, picked up the phone to answer a call in 2001, he could barely understand the man speaking on the other line. “I could not hear his voice…
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New NIH grant to study language use as potential predictor of neurodegenerative disorder in FMR1 premutation carriers
A new study will investigate if language differences can predict the development of a neurodegenerative disorder in people that carry a premutation of the gene FMR1.
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Pioneering research brings potential Parkinson’s disease treatment one step closer
Over two decades of fundamental research in Parkinson’s disease led by Su-Chun Zhang, MD, PhD, professor of neuroscience and neurology at the University of Wisconsin-Madison and Waisman investigator, has culminated in the…
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A science trailblazer retires: Stem cell researcher James Thomson’s legacy changed the future of biology
James Thomson helped the scientific world turn its attention to the shape-shifting stem cells that give rise to all of the building blocks of complex living organisms, from skin and bone, to…
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Individualized brain cell grafts reverse Parkinson’s symptoms in monkeys
Grafting neurons grown from monkeys’ own cells into their brains relieved the debilitating movement and depression symptoms associated with Parkinson’s disease, researchers at the University of Wisconsin–Madison reported today.
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Stem cells can repair Parkinson’s-damaged circuits in mouse brains
The mature brain is infamously bad at repairing itself following damage like that caused by trauma or strokes, or from degenerative diseases like Parkinson’s. Stem cells, which are endlessly adaptable, have offered…
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New initiative to study Parkinson disease
Su-Chun Zhang, MD, PhD, the Steenbock Professor in Behavioral and Neural Sciences at the University of Wisconsin-Madison and Waisman Center investigator, is part of an interdisciplinary team of researchers selected by the…
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UW-Madison biomanufacturer offers essential gene-transfer capacity
Adeno-associated virus (AAV) is used to insert replacement genes, and its role in genetic therapy trials is expanding quickly, says Carl Ross, managing director of Waisman Biomanufacturing. The AAV production reflects the…
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A decade after stem cell feat, research ramps up
A decade after scientists announced the development of induced pluripotent stem cells, Waisman investigators, including Su-Chun Zhang and David Gamm, continue to use these cells to research and develop potential therapies for…
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Brain cells by the billions
Leaders of the University of Wisconsin–Madison lab that first transformed human stem cells into brain cells have started a company that produces and sells specialized neurons to drug researchers. BrainXell develops neurons…
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Waisman researchers part of several UW2020 awards
Several research and infrastructure projects featuring Waisman Center researchers as the primary or co-investigator have been selected for the second round of funding through the UW2020
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Cell transplant treats Parkinson’s in mice under control of designer drug
A University of Wisconsin—Madison neuroscientist has inserted a genetic switch into nerve cells so a patient can alter their activity by taking designer drugs that would not affect any other cell.
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Single brain cells reveal genes controlling formation, development
In one of the first studies to “read” the genetic activity inside individual brain cells, University of Wisconsin—Madison neuroscientist Xinyu Zhao has identified the genetic machinery that causes maturation in a young…
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Transplanted brain cells in monkeys light up personalized therapy
For the first time, scientists have transplanted neural cells derived from a monkey’s skin into its brain and watched the cells develop into several types of mature brain cells, according to the…
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After 40 years, Waisman Center still at forefront of research on the brain
The telegram from President John F. Kennedy to University of Wisconsin President Fred Harrington was both eerie and visionary. Eerie because it was delivered Nov. 20, 1963 – just two days before…
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Waisman Center: Celebrating 40 years of advancing knowledge about developmental disabilities
Although its roots are deeper, going back to its earliest iteration as the Joseph P. Kennedy, Jr. Memorial Laboratories in the early 1960s, the Waisman Center this year celebrates 40 years of…
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Human brain’s most ubiquitous cell cultivated in lab dish
Long considered to be little more than putty in the brain and spinal cord, the star-shaped astrocyte has found new respect among neuroscientists who have begun to recognize its many functions in…
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