Insulin resistance (IR) has been related to reduced cerebral glucose metabolism in regions identified as hypometabolic in Alzheimer’s clinical syndrome. Insulin secretion (IS) has been less studied than IR despite findings that decreased IS is an early indicator of future type 2 diabetes and a potential predictor of Alzheimer’s clinical syndrome.
A new paper published by Anita Bhattacharyya, PhD, assistant professor of cell and regenerative biology at UW-Madison and a Waisman investigator, reveals that the differences in brain structure in individuals with Down syndrome (DS or Trisomy 21) may be due to disrupted signaling pathways that alter brain development to result in the incorrect number or placement of cells in the brain.
Photoreceptors (PRs) are the primary visual sensory cells, and their loss leads to blindness that is currently incurable. Although cell replacement therapy holds promise, success is hindered by our limited understanding of PR axon growth during development and regeneration.
People with metabolic disorders who require formula to ensure adequate nutrition are among those dealing with a months long shortage — the Waisman Center at UW-Madison is seeking to help source alternatives, even as such options can be stressful.
UW-Madison recently announced the second round of recipients for the Research Forward program with Seth Pollak, PhD, a Waisman investigator among them.
Quantitative neuroimaging studies in twin samples can investigate genetic contributions to brain structure and microstructure
Intellectual and Developmental Disabilities (IDDs), such as Down syndrome, Fragile X syndrome, Rett syndrome, and autism spectrum disorder, usually manifest at birth or early childhood.
From physicians to speech language pathologists, to social workers and nutritionists, there are a wide range of professionals that help to support the services and supports that help people with IDD to thrive.
Title: Anatomic development of the upper airway during the first five years of life: A three-dimensional imaging study Legend: Illustration of the airway regions and measurements. The four airway regions [Nasopharynx (blue); Oropharynx (red); Laryngopharynx …
The start of the Waisman Center’s Bone Dysplasia Clinic was a case of serendipity. It was 1980 and Richard Pauli, MD, a pediatric geneticist, had just arrived at UW-Madison. Over the course of the year, Pauli settled into his new role at UW Hospital. Then in 1981, he was approached by radiologist Len Langer, MD, with a strange request.