How advanced MRI paired with neuropsychological testing shed light on how Temple Grandin’s brain processes the world

Temple Grandin, PhD, is likely the most well-known living autistic individual, both nationally and internationally. She is not only a renowned scientist and educator but also an esteemed author and advocate. Across the decades of her life, she has spent considerable time on her personal pursuit of knowledge and understanding about autism and the ways that it influences her perception and interpretation of the world around her. As a Distinguished Professor of Animal Science at Colorado State University, her professional pursuits involve studying animal behavior and, in particular, designing humane livestock-handling systems.

The Baby Badger Network seeks to make genetic testing more accessible to critically-ill newborns throughout Wisconsin

In Wisconsin, a new initiative is transforming the landscape of neonatal care by making genetic testing more accessible for critically-ill newborns. The Baby Badger Network (BBN) is a team effort among healthcare providers to break down barriers to genetic testing and ensure timely diagnosis and care for their most vulnerable patients.

New algorithm helps decipher complex biological data to advance neurodevelopmental research

A new machine learning algorithm developed at UW-Madison is helping researchers untangle a complex puzzle: the molecular mechanisms behind developmental disabilities and neurodegenerative diseases. COSIME, created by the lab of Waisman investigator Daifeng Wang, PhD, associate professor of biostatistics and medical informatics, and computer sciences, offers a powerful new way to integrate and interpret multiple types of biological data which can give scientists a clearer view of how different cellular clues come together to shape disease outcomes.

New research reinforces the link between a cellular quality control system and rare forms of autism

Just like a car factory relies on inspectors to ensure that every vehicle is built correctly, cells depend on internal quality control systems to keep proteins functioning as they should. New research from Waisman Center investigator Luigi Puglielli, MD, PhD, professor of medicine at the University of Wisconsin-Madison, reveals that disruptions in one such system—the endoplasmic reticulum’s acetylation pathway—can lead to rare forms of autism and progeria, offering fresh insights into the cellular roots of these complex conditions.