The endoplasmic reticulum acetylation machinery has emerged as a new branch of the larger endoplasmic reticulum quality control system.
Earliest signs of neurodegeneration in Down syndrome detected shortly after birth, new Waisman study shows
Signs of neurodegeneration in individuals with Down syndrome may start as early as birth, a critical stage of brain development, a new study shows. The research, from investigators at the Waisman Center, University of Wisconsin-Madison, provides an atlas of early brain development in Down syndrome that could inform potential targeted treatments to address the developmental and degenerative aspects of the condition.
Ability, not disability: UW allies highlight advocacy in light of Autism Acceptance Month
April is Autism Acceptance Month — a time to recognize those on the autism spectrum, provide support, improve access to services and celebrate neurodiverse identities. Autism is a developmental disability, meaning it displays itself during the pediatric period, according to senior scientist at the University of Wisconsin Waisman Center and director of the University Center for Excellence in Developmental Disabilities Leann DaWalt.
Caroline A Niziolek, PhD – Slide of the Week
Young adult speakers can be induced to increase the acoustic contrast between vowels through exposure to a nonuniform auditory “centralization” feedback perturbation that makes vowels sound less distinct from one another.
New tool for researchers makes it easier to analyze individual neurons
The electrical properties of a neuron paint a picture of its development and function. A new user-friendly and accessible tool developed at the Waisman Center allows scientists to analyze the electrical activity of individual neurons – rather than clusters – using a process known as spike sorting. The free tool is available online for other researchers to access.
Drug shifts a key hormone after newborn brain injury – but only in females
A blood test alone cannot tell the full story of what’s happening inside a newborn’s brain after a brain injury. New research from the Waisman Center at the University of Wisconsin-Madison suggests that the hippocampus—a brain region critical for learning and memory—maintains its own powerful, locally regulated steroid environment during early development and after brain injury.
Eagles Autism Foundation funds new research on use of nanotechnology to deliver gene-editing tools to the brain
A new research study at the Waisman Center has been funded by the Eagles Autism Foundation to develop a precise, safe, and broadly applicable method for correcting a single-gene mutation associated with symptoms of autism spectrum disorders including learning deficits, anxiety, depression, and reduced social interactions.
Gallery Walk: The Pandemic Cancelled It, and They Never Brought It Back
The gallery walk goes from Monday, April 6 through Thursday, April 30, 2026 and will be accessible during regular business hours in the John D. Wiley Conference Center hallway at the Waisman Center on the second floor, north tower.
Ruth Litovsky, PhD – Slide of the Week
We studied Cognitive load by measuring both speech understanding in noise and pupillometry (Pupil dilation).
Friendship at the museum: How science helps kids make friends through play
Shutts uses what she learns in her research as a social scientist to influence how kids in the community learn through play at the museum. Her area of expertise is how children make sense of their social world, and how to help kids build their social skills. In an attempt to oversimplify her work, you could say she’s an expert in friendships.