Title: Infant temperament in twins: Heritability, stability, and parents’ emotional experiences Legend: We used Latent Profile Analyses to derive four profiles of infant temperament from 990 twins at 6 and 12 months of age using observed …
David Gamm, MD, PhD – Slide of the Week
Title: Investigating Cone Photoreceptor Development using Patient-Derived NRL Null Retinal Organoids Legend: The transcription factor NRL is required for normal rod photoreceptor development. In retinal organoids derived from wildtype, NRL+/+ iPSCs (c-h), 80% of photoreceptors …
Peter Ferrazzano, MD – Slide of the Week
By identifying MRI biomarkers in animal models of pediatric brain injury, Waisman investigator Peter Ferrazzano hopes to provide a means for selecting the patients most likely to benefit from a particular neuroprotective intervention in subsequent clinical trials.
Susan Ellis Weismer, PhD – Slide of the Week
In typical development, listeners can use semantic content of verbs to facilitate incremental language processing-a skill that is associated with existing language skills. Studies of children with ASD have not identified an association between incremental language processing in semantically-constraining contexts and language skills, perhaps because participants were adolescents and/or children with strong language skills.
Viji Easwar, PhD – Slide of the Week
EEG is currently the only clinically feasible method to evaluate hearing in infants and children who are unable to participate in behavioral hearing tests. We modified naturally spoken vowels and fricatives to elicit envelope following responses (EFR) at low, mid and high frequencies–the prime spectral regions essential for speech understanding, and speech and language development.
How do little ears with hearing loss hear speech?
Our research study is investigating how children’s brains process speech and how hearing loss during childhood influences the processing of speech. In this study, 5-17-year-old children with normal hearing and hearing loss will undergo a …
Darcie Moore, PhD – Slide of the Week
Neurogenesis is thought to be sustained throughout life through the constant regulation of neural stem cell (NSC) quiescence exit, a time in which a NSC enters the cell cycle to generate more neural stem cells and/or other neural cell types. One critical component of NSC quiescence exit is the clearance of aggregated proteins.
Navigating a Brighter Future for Youth with Disabilities and Their Families
Helping youth with disabilities pursue post-high school employment and education opportunities can mean piecing together services from a broad range of agencies and organizations. This can be a challenge for anyone, but for low-income families, …
New Researcher Uses Machine Learning to Decode Genomic Information
Recent advances in genome sciences — the study of an organism’s complete set of DNA — present a golden opportunity to identify the genetic causes and underlying mechanisms of intellectual and developmental disabilities. These discoveries …
Qiang Chang, PhD – Slide of the Week
Rett syndrome (RTT) is a severe neurodevelopmental disease caused by mutations in the methyl-CpG binding protein 2 (MECP2) gene. Although altered interneuron development and function are clearly demonstrated in RTT mice, a particular mode of inhibition, tonic inhibition, has not been carefully examined.