New research by University of Wisconsin–Madison scientists reveals how a cellular filament helps neural stem cells clear damaged and clumped proteins, an important step in eventually producing new neurons.
Year: 2020
Jan Greenberg, PhD – Slide of the Week
Expressed emotion (EE) is a measure of the family’s emotional climate and has been shown to be associated with a range of symptoms and psychiatric outcomes in individuals with various disabilities. In addition, growing evidence suggests that high levels of family distress are associated with high EE.
Routine test reveals rare diseases
“The newborn screening is most likely the first test of your child’s life,” says Mei Baker, MD, co-director of the Newborn Screening Laboratory at the Wisconsin State Lab of Hygiene and a Waisman Center affiliate investigator.
Catherine Kanter named speech-language pathologist of the year
“I then found in speech-language pathology a wonderful marriage of my love for language and communication and helping individuals with disabilities, and came to UW-Madison to complete my graduate degree,” says Kanter, who has worked as a full-time speech-language pathologist, or SLP, at the Waisman Center since June 2018.
H. Hill Goldsmith, PhD – Slide of the Week
We used Latent Profile Analyses to derive four profiles of infant temperament from 990 twins at 6 and 12 months of age using observed infant behavior. Parents reported on their own emotional experiences.
David Gamm, MD, PhD – Slide of the Week
Loss of photoreceptors through disease or injury is a leading cause of vision loss. Emerging stem cell-based strategies aimed at treating these conditions would benefit from an improved understanding of the complex gene-expression patterns directing photoreceptor development.
Peter Ferrazzano, MD – Slide of the Week
By identifying MRI biomarkers in animal models of pediatric brain injury, Waisman investigator Peter Ferrazzano hopes to provide a means for selecting the patients most likely to benefit from a particular neuroprotective intervention in subsequent clinical trials.
Susan Ellis Weismer, PhD – Slide of the Week
In typical development, listeners can use semantic content of verbs to facilitate incremental language processing-a skill that is associated with existing language skills. Studies of children with ASD have not identified an association between incremental language processing in semantically-constraining contexts and language skills, perhaps because participants were adolescents and/or children with strong language skills.
Viji Easwar, PhD – Slide of the Week
EEG is currently the only clinically feasible method to evaluate hearing in infants and children who are unable to participate in behavioral hearing tests. We modified naturally spoken vowels and fricatives to elicit envelope following responses (EFR) at low, mid and high frequencies–the prime spectral regions essential for speech understanding, and speech and language development.
Darcie Moore, PhD – Slide of the Week
Neurogenesis is thought to be sustained throughout life through the constant regulation of neural stem cell (NSC) quiescence exit, a time in which a NSC enters the cell cycle to generate more neural stem cells and/or other neural cell types. One critical component of NSC quiescence exit is the clearance of aggregated proteins.