Category: Alzheimer’s Disease

‘We built a brain roadmap for each person’: New AI-driven tools help decode Alzheimer’s disease at the cellular level

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Identifying the cells connected with Alzheimer’s symptoms could result in new treatments for the disease. By Emily Leclerc and Charlene N. Rivera-Bonet Alzheimer’s disease is complex, presenting and progressing in so many different ways in individual patients that it’s difficult for scientists to study. Now, researchers at the University of Wisconsin–Madison have developed AI-driven bioinformatics …

Puerto Rico to become a site for The Alzheimer Biomarker Consortium – Down syndrome

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Puerto Rican families have started traveling to Wisconsin to be part of the research study, but the goal is to build the infrastructure to eventually conduct the studies on the island.

Changes in walking patterns could be an important new screening tool for Alzheimer’s in individuals with Down syndrome

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Individuals with Down syndrome have a 90% lifetime risk of developing Alzheimer’s disease.

How AI is advancing medical research

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Waisman Investigator Daifeng Wang, PhD, associate professor of biostatistics and medical informatics, was featured on this article by the School of Medicine and Public Health on how artificial intelligence (AI) is advancing medical research at UW.

New algorithm helps decipher complex biological data to advance neurodevelopmental research

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A new machine learning algorithm developed at UW-Madison is helping researchers untangle a complex puzzle: the molecular mechanisms behind developmental disabilities and neurodegenerative diseases. COSIME, created by the lab of Waisman investigator Daifeng Wang, PhD, associate professor of biostatistics and medical informatics, and computer sciences, offers a powerful new way to integrate and interpret multiple types of biological data which can give scientists a clearer view of how different cellular clues come together to shape disease outcomes.

New study shows nuanced and complex relationship between tau and brain cell loss in Alzheimer’s Disease

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[uw-reusable-content id=’29797′] At a Glance Loss of synapses, the connections between neurons that allow them to communicate, is a primary driver of cognitive decline in Alzheimer’s disease. Researchers expected a strong connection between synapse loss and tau buildup but the relationship was more nuanced than expected. Researchers found weak connections between tau buildup and synapse …

A family’s commitment to Down syndrome research at the Waisman Center spans four decades and counting

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When Heather Huismann was in middle school she called the police on her teacher. “He was not teaching me very well,” Heather says.

UW-Madison’s Cool Science Image Contest: Waisman winners

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Matt Zammit, PhD, Waisman scientist in the Brain Imaging Core, and affiliate investigator Erik Dent, PhD, are both winners of UW-Madison’s Cool Science Image Contest.

UW-Madison researchers first to 3D-print functional human brain tissue

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A team of University of Wisconsin–Madison scientists has developed the first 3D-printed brain tissue that can grow and function like typical brain tissue.

Fit Families makes exercise accessible to children with disabilities

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Families and their children with intellectual and developmental disabilities often face many barriers to getting accessibility to exercise.