Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
Title: Sensory subtypes in children with autism using a latent profile transition analysis Legend: Four clinically distinct and homogeneous sensory subtypes were found to characterize children with autism spectrum disorder (ASD) in a large longitudinal national sample and also shown to be stable (91%) over one year. The Mild Subtype (N = 308, 29%) described …
Titel: Imaging of TFG, a protein implicated in neurodegenerative disease, across a variety of scales Legend: Staining of TFG (green) and a marker of the endoplasmic reticulum (red) in human epithelial cells (left). The localization of TFG was further defined by immunogold electron microscopy (15 nm gold particles), highlighting its accumulation among ER-derived transport carriers …
Title: Classroom observations of social interactions between high school students with significant disabilities and their general education peers Legend: The average rate (number) of interactions per hour for focus students with significant disabilities with any general education classmate across peer support and comparison groups during pre (no intervention for both groups) and post (peer support intervention; …
The Friends of the Waisman Center held its 20th annual benefit concert on Friday, May 1. This was a milestone event celebrating not only the 20th concert, but also the 40th anniversary of the Friends of the Waisman Center.
Title: Multiple contrast MRI with retrospective motion correction Legend: Representative example of multiple image contrasts from a new brain imaging technique MPnRAGE developed in the Alexander Lab in the Waisman Brain Imaging Core. The MPnRAGE method can generate multiple inversion recovery contrasts, quantitative T1 relaxometry, and tissue specific (gray matter or white matter) maps. Whole …
May is ALS awareness month and Waisman Center investigator Su-Chun Zhang, MD, PhD, uses stem cells from ALS patients to uncover the cause of ALS and screen drugs to treat the disease. Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord that control muscle movement. …
