Alzheimer’s Biomarkers Consortium – Down Syndrome: ABC-DS (Christian & Hartley)

The National Institutes of Health-funded Alzheimer’s Biomarkers Consortium – Down Syndrome (ABC-DS), a large multi-center research initiative to find biomarkers to track Alzheimer’s disease in Down syndrome. The Waisman Center is part of this multi-site …

New NIH-funded initiative will examine Alzheimer’s disease in people with Down syndrome

A team of researchers at the University of Wisconsin–Madison is part of a new multi-institution effort to better understand Alzheimer’s disease in adults with Down syndrome. Adults with Down syndrome are at high risk for …

Andrew Alexander, PhD – Slide of the Week

Demonstration of the ability of MPnRAGE to correct for severe motion artifacts in a 7 year old girl.  Retrospective motion correction greatly reduced motion-induced blurring in both  structural T1-weighted images and quantitative T1 maps.  The correction greatly improves the reliability of brain imaging measurements in children.  The plots indicate the estimated amount of head motions that were corrected.

Doug Dean, III, PhD – Slide of the Week

White matter microstructure, essential for efficient and coordinated transmission of neural communications, undergoes pronounced development during the first years of life, while deviations to this neurodevelopmental trajectory likely result in alterations of brain connectivity relevant to behavior. Hence, systematic evaluation of white matter microstructure in the normative brain is critical for a neuroscientific approach to both typical and atypical early behavioral development.