Advancing knowledge of human development, developmental disabilities, and neurodegenerative diseases.
AT A GLANCE: Clinical trials serve as the crucial bridge between groundbreaking laboratory research and the eventual approval of new treatments or interventions. At the Waisman Center, researchers like Albee Messing, VMD, PhD, and David Gamm, MD, PhD have dedicated decades to transforming innovative ideas into potential therapies, now undergoing rigorous testing to ensure their …
By Emily Leclerc, Waisman Science Writer One of Carl Ross’s favorite stories is actually an account of one of his failures. In the early 2000s Ross, the former managing director of Waisman Biomanufacturing (WB), was working to make a rhinovirus (the virus that is responsible for the common cold) that could be used to test …
After an extensive national search, Chris Bartley was recently selected as the new managing director of Waisman Biomanufacturing (WB). Bartley most recently served as the facility’s interim director.
James Thomson helped the scientific world turn its attention to the shape-shifting stem cells that give rise to all of the building blocks of complex living organisms, from skin and bone, to hearts and blood, to neurons and brains.
Waisman Biomanufacturing at the University of Wisconsin–Madison will begin manufacturing a new drug to treat and prevent COVID-19, developed by California-based biotech company GigaGen. The drug, called GIGA-2050, uses a new approach similar to treating COVID-19 patients with convalescent plasma, or blood products from people recovering (convalescing) from an infection. Waisman Biomanufacturing was created to facilitate just this sort of development and testing of new types of drugs.
Waisman Biomanufacturing at the University of Wisconsin–Madison is partnering with Heat Biologics to produce a COVID-19 vaccine for phase 1 and phase 2 clinical trials. Phase 1 trials could begin in early 2021 and UW–Madison may be a trial site.
As of this week, a phase one clinical trial to test a potential new Ebola vaccine developed by researchers at the University of Wisconsin–Madison is underway in Japan. Fifteen healthy young men* will receive two doses of the experimental vaccine. If the first group tolerates the vaccine, an additional group of up to 20 volunteers will receive a higher dose of the vaccine.
Adeno-associated virus (AAV) is used to insert replacement genes, and its role in genetic therapy trials is expanding quickly, says Carl Ross, managing director of Waisman Biomanufacturing. The AAV production reflects the Waisman lab’s growing importance in the biopharma business, as it’s the only facility on campus meeting FDA “good manufacturing practices” rules for large-scale manufacturing of biological therapies.
Waisman Biomanufacturing has produced and helped bring to clinical trial a vaccine that aims to prevent infection by the human immunodeficiency virus (HIV), which causes AIDS. The vaccine was developed by researchers at the University of Massachusetts Medical School and is set to undergo a Phase I clinical trial at four sites in the United …
Waisman Biomanufacturing and Waisman affiliate investigators Randolph Ashton and Krishanu Saha will be part of a new engineering research center that will develop transformative tools and technologies for the consistent, scalable and low-cost production of high-quality living therapeutic cells. Such cells could be used in a broad range of life-saving medical therapies now emerging from …
