Our machine-learning framework, brain and organoid manifold alignment (BOMA), first performs a global alignment of developmental gene expression data between brains and organoids.
Slide of the Week
Houri K. Vorperian, PhD – Slide of the Week
Atypical vowel production contributes to reduced speech intelligibility in children and adults with Down syndrome (DS)
Brittany G. Travers, PhD – Slide of the Week
The goal of this research was to determine how sensory features, such as increased or decreased sensitivity to the environment, are associated with the brainstem in autistic and non-autistic children
John Svaren, PhD – Slide of the Week
Schwann cells play a critical role after peripheral nerve injury by clearing myelin debris, forming axon-guiding bands of Büngner, and remyelinating regenerating axons.
Audra Sterling, PhD – Slide of the Week
Expressive language impairments are common among school-age boys with fragile X syndrome (FXS) and autistic boys.
André Sousa, PhD – Slide of the Week
The granular dorsolateral prefrontal cortex (dlPFC) is an evolutionary specialization of primates that is centrally involved in cognition. We assessed more than 600,000 single-nucleus transcriptomes from adult human, chimpanzee, macaque, and marmoset dlPFC.
UCEDD – Slide of the Week
This study examines the relationship between the early identification of hearing loss and language outcomes for deaf/hard of hearing (D/HH) children, with bilateral or unilateral hearing loss and with or without additional disabilities.
Kris Saha, PhD – Slide of the Week
Leber Congenital Amaurosis (LCA16) is a progressive vision loss disorder caused by point mutations in the KCNJ13 gene, which encodes an inward-rectifying potassium channel, Kir7.1.
Jenny Saffran, PhD – Slide of the Week
Online data collection methods pose unique challenges and opportunities for infant researchers.
Luigi Puglielli, MD, PhD – Slide of the Week
N ε-lysine acetylation within the lumen of the endoplasmic reticulum is a recently characterized protein quality control system that positively selects properly folded glycoproteins in the early secretory pathway.